Naslov
Cryptococcus neoformans meningoencephalitis in a patient with idiopathic CD4+ T lymphocytopenia

Autori
Pavić, Ivica ; Cekinović, Đurđica ; Begovac, Josip ; Maretić, Tomislav ; Čivljak, Rok ; Trošelj Vukić, Biserka

Izvornik
Collegium antropologicum (0350-6134) 37 (2013), 2; 619-623

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni

Ključne riječi
Cryptococcal meningoencephalitis; CD4+ T cell immunodeficiency; HIV

Sažetak
Cryptococcus neoformans is a leading cause of invasive cryptoccocal infections which include meningitis/meningoencephalitis, cerebral cryptococcoma, invasive pulmonary and mediastinal infection. Invasive infection is mainly diagnosed in immunocompromised patients, especially in HIV- infected individuals. There is a rising number of patients with invasive cryptococcal infections in immunocompromised patients who are HIV-negative. Among several primary immunodeficiency syndromes, considered as possible reasons for these invasive infections, idiopathic CD4+ T lymphocytopenia (ICL) is most frequently diagnosed. The pathogenesis of this rare syndrome is still unknown, while its clinical spectrum ranges from an asymptomatic laboratory abnormality to life- threatening opportunistic infections. Here we present an HIV-negative young man suffering from cryptococcal meningoencephalitis in whom ICL was diagnosed.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA