Naslov
The trends in incidence and survival of primary CNS tumours in the population of Primorje-Gorski Kotar region-Croatia (1977-2000)

Autori
Tuškan-Mohar, Lidija ; Weiner-Črnja, Mima, Antončić, Igor ; Willheim, Ksenija ; Jurjević, Ante ; Materljan, Eris

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
European Journal of Neurology (Supplement) / - , 2002, 103-104

Skup
6th Congress of the European Federation of Neurological Societies EFNS

Mjesto i datum
Beč, Austrija, 26.10.2002. - 29.10.2002

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
primary CNS tumours; trends in incidence; survival; Primorje-Gorski Kotar region; Croatia

Sažetak
Introduction: Descriptive epidemiology of primary CNS tumours has been the subject of several studies, indicating a possible increase in CNS tumour rates. The aim of this study was to evaluate incidence and survival of patients with primary CNS tumours diagnosed between 1977 and 2000 in our Region. Methods: Between 1977 and 2000, 911 registered patients with diagnosis of primary CNS tumours were reviewed. The incidence rates by gender, age, tumour location and histological type were calculated for whole and for two times period of investigation (1977-1986 and 1991-2000). Temporal trends were analysed. Survival rates at 1 and 5 years were also estimated. Results: Eight-six percent of the tumours were pathohistologically confirmed and 14% were clinically verified. Total annual incidence of all CNS primary tumours was 11.5/100 000/year, (10.7 for intracranial and 0.5 for intarsia location). Mean age at diagnosis year was 50.7 the most common tumour types were glioblastoma (26.1%). It was an increasing trend of incidence rate from 9.69/100 000/year (1977-1986) to 12.19/100 000/year (1991-2000). The most increase incidence was noted for meningiomas (from 1.0 to 3.17). The 1-year survival for all tumours was 60.5% (95%CI=57.2-65.8) and the 5 years survival was 52.2% (95%CI=48.7-55.7). Comparing the first and the second time period, significant improvements occurred in survival for all tumours. Conclusion: The results of this study confirm the observation made in other countries that the incidence of primary brain tumours is increasing, and the further research into their aetiology and treatment is required.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA