Naslov
Placental cadmium concentration as an indicator of maternal tobacco smoking

Autori
Sekovanić, Ankica ; Jurasović, Jasna ; Orct, Tatjana ; Brajenović, Nataša ; Brčić Karačonji, Irena ; Mikolić, Anja ; Sulimanec Grgec, Antonija ; Stasenko, Sandra ; Piasek, Martina

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
X ISTERH Conference Trace Element Research on Health and Diseases ; u: Journal of Trace Elements in Medicine and Biology 27 (2013) (S1) / - : Elsevier, 2013, 47-47

Skup
ISTERH 2013 Conference "Trace Element Research on Health and Diseases" (10 ; 2013)

Mjesto i datum
Tokyo, Japan, 18.11.2013. - 22.11.2013

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
cadmium; nicotine; noninvasive biomarker; placenta; postpartum women

Sažetak
Tobacco smoke is a mixture of toxic chemicals with reproductive endocrine-disrupting potential including cadmium. We monitored tobacco smoke exposure in healthy subjects (mean age 28) after vaginal delivery at term in a clinical hospital. Based on self-ascertainment and maternal hair nicotine concentrations (measured in min. 12 cm long samples by GC-MS) 3 groups were identified: 32 smokers, 35 passive smokers and 19 nonsmokers. Cadmium concentrations were analyzed (by ICP-MS) in maternal blood, umbilical cord blood and the placenta. We found increases in hair nicotine of ca. 7 times and maternal blood cadmium of ca. 4 times in smokers vs. passive smokers and nonsmokers. Cord blood cadmium concentrations were equally low (< 0.1 ppb) in all of the groups. Placental cadmium was significantly higher in smokers than in passive smokers and nonsmokers. In conclusion, apart from hair nicotine, placental cadmium could serve as an alternative noninvasive marker of active tobacco smoking in postpartum smokers.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Javno zdravstvo i zdravstvena zaštita

Napomena
Priopćenju je dodijeljena nagrada 'ISTERH Investigator Award' međunarodnog društva International Society for Trace Element Research in Humans tijekom održavanja kongresa X ISTERH - Trace Element Research on Health and Diseases, Tokyo, Japan za izvrsno izlaganje istraživanja.

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