Naslov
Human West Nile virus infection in eastern Croatia, August-September, 2012

Autori
Vilibić-Čavlek, Tatjana ; Pem-Novosel, Iva ; Gjenero-Margan, Ira ; Pandak, Nenad ; Perić, Ljiljana ; Barbić, Ljubo ; Kožul, Karlo ; Listeš, Eddy ; Jelčić, Pavle ; Stevanović, Vladimir ; Savini, Giovanni

Izvornik
Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti (1330-5301) 39 (2013); 73-80

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
West Nile virus ; outbreak ; seroprevalence ; Croatia

Sažetak
In the period from 6 to 21 September, Croatia reported the first clinical cases of human West Nile virus (WNV) neuroinvasive infection in three counties (Brod-Posavina, Osijek-Baranja and Vukovar-Srijem County). The first case was most probably imported from Serbia where the patient resided during the incubation period, while the others represent autochthonous cases. Five patients presented with meningoencephalitis and two with meningoencephalitis followed by acute flaccid paralysis. In all samples WNV IgG and/or IgM antibodies were detected using enzyme-linked immunosorbent assay (ELISA) and confirmed by plaque-reduction neutralization (PRNT) and micro-neutralization test (MNT). Following the outbreak, a total of 178 serum samples were collected from healthy inhabitants of Osijek-Baranja County where the incidence of cases were highest. WNV IgG antibodies were detected by ELISA in 4 (2.2%) participants indicating the increased WNV circulation in this area in comparison with season 2011 resulting in the first reported clinical cases.

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita

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