Pregled bibliografske jedinice broj: 642452
Structure of microtubule network in neuronal cell after modulated RF exposure
Structure of microtubule network in neuronal cell after modulated RF exposure // 40th Annual Meeting of the European Radiation Research Society book of abstracts
Dublin, Irska, 2013. (predavanje, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 642452 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Structure of microtubule network in neuronal cell after modulated RF exposure
Autori
Pavicic, Ivan ; Marjanovic, Ana Marija ; Trosic, Ivancica
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
40th Annual Meeting of the European Radiation Research Society book of abstracts
/ - , 2013
Skup
40th Annual Meeting of the European Radiation Research Society
Mjesto i datum
Dublin, Irska, 01.09.2013. - 05.09.2013
Vrsta sudjelovanja
Predavanje
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
microtubule network; cell growth; mobile phone radiation; 915 MHz; in vitro
Sažetak
The influence of GSM (Global System of Mobile) modulated radiofrequency (RF) radiation on microtubule network and proliferation of continuous culture of neuronal cell line SH-SY5Y was estimated. SH-SY5Y cells were exposed in triplicate to GSM modulated RF field frequency of 915 MHz inside the Gigahertz Transversal Electromagnetic Mode cell (GTEM-cell) for 1, 2, and 3 hours. The RF field was generated by the signal generator combined with power amplifier and signal modulator. The electric field strength was adjusted to 10 V/m. The average specific absorption rate (SAR) was calculated to be 0.23 W/kg. Negative- and positive cell controls were included into the experiment. The structure of microtubule proteins was determined by means of indirect immunocytochemistry methodology. Cell growth was recognised by cell counts determined for each hour of exposure during ten post-exposure days. Significant alterations of microtubule structure were observed after three hours of exposure. In comparison to the controls, a significant decrease in cell growth was found three days after three-hour of exposure to radiation. In conclusion, regarding the exposure time, 915 MHz GSM modulated RF radiation affects microtubule network and consequently growth of neuronal cell line SH-SY5Y.
Izvorni jezik
Engleski
Znanstvena područja
Biologija, Temeljne medicinske znanosti
POVEZANOST RADA
Projekti:
022-0222411-2406 - BIOLOŠKI POKAZATELJI DJELOVANJA ELEKTROMAGNETSKOG NEIONIZIRAJUĆEG ZRAČENJA (Trošić, Ivančica, MZOS ) ( CroRIS)
Ustanove:
Institut za medicinska istraživanja i medicinu rada, Zagreb