Naslov
Occupational and non-occupational allergic contact dermatitis : a follow-up study

Autori
Macan, Jelena ; Rimac, Davor ; Kežić, Sanja ; Varnai, Veda Marija

Izvornik
Dermatology (Basel) (1018-8665) 227 (2013), 4; 321-329

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
occupational contact dermatitis; prognosis; prevention of occupational skin diseases; asymptomatic contact sensitization; patch testing

Sažetak
The aim of this study was to obtain insight into the clinical course and prognosis of allergic contact dermatitis (ACD), including potential effects of genetic and environmental factors. Eighty-two patients with previously defined ACD acquired occupationally (OACD) or non-occupationally (NOACD) were patch retested and evaluated for the presence of persistent eczema, atopy and filaggrin mutations. The crude risk for the persistence of a positive patch test (PT) reaction was 6.3 times higher (95% CI 3.63-11.0) for PT reactions assessed as '+++' compared to '++' reactions at the first PT. Among the categories of OACD, NOACD, age, gender, atopy, and the number of positive PT reactions at the first and second PT, only OACD (OR 10.0, 95% CI 1.95-51.2) and number of positive PT reactions at retesting (OR 3.85, 95% CI 1.57-9.44) were found to be predictors of persistent eczema. Occupationally acquired contact allergy was emphasized as the most important factor in predicting poor prognosis of ACD.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Javno zdravstvo i zdravstvena zaštita

POVEZANOST RADA