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Pregled bibliografske jedinice broj: 631380

Estimation of fractal dimension in differential diagnosis of pigmented skin lesions

Aralica, Gorana; Milošević, Danko; Konjevoda, Paško; Seiwerth, Sven; Štambuk, Nikola
Estimation of fractal dimension in differential diagnosis of pigmented skin lesions // Chaos and Complex Systems : Proceedings of the 4th International Interdisciplinary Chaos Symposium / Stavrinides, Stavros ; Banerjee, Santo ; Caglar, Hikmet ; Ozer, Mehmet (ur.).
Berlin: Springer, 2013. str. 233-238 doi:10.1007/978-3-642-33914-1_30 (poster, međunarodna recenzija, cjeloviti rad (in extenso), znanstveni)

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Naslov
Estimation of fractal dimension in differential diagnosis of pigmented skin lesions

Autori
Aralica, Gorana ; Milošević, Danko ; Konjevoda, Paško ; Seiwerth, Sven ; Štambuk, Nikola

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni

Izvornik
Chaos and Complex Systems : Proceedings of the 4th International Interdisciplinary Chaos Symposium / Stavrinides, Stavros ; Banerjee, Santo ; Caglar, Hikmet ; Ozer, Mehmet - Berlin : Springer, 2013, 233-238

ISBN
978-3-642-33914-1

Skup
4th International Interdisciplinary Chaos Symposium on Chaos and Complex Systems

Mjesto i datum
Antalya, Turska, 29.04.2012. - 02.05.2012

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
fractal ; dimension ; diagnosis ; skin ; lesions ; melanoma

Sažetak
Medical differential diagnosis is a method of identifying the presence of a particular entity (disease) within a set of multiple possible alternatives. The significant problem in dermatology and pathology is the differential diagnosis of malignant melanoma and other pigmented skin lesions, especially of dysplastic naevi. Malignant melanoma is the most malignant skin neoplasma, with increasing incidence in various parts of the world. It is hoped that the methods of quantitative pathology, i.e. morphometry, can help objectification of the diagnostic process, since early discovery of melanoma results in 10-year survival rate of 90%. The aim of the study was to use fractal dimension calculated from the perimeter-area relation of the cell nuclei as a tool for the differential diagnosis of pigmented skin lesions. We analyzed hemalaun-eosin stained pathohistological slides of pigmented skin lesions: intradermal naevi (n = 45), dysplastic naevi (n = 47), and malignant melanoma (n = 50). It was found that fractal dimension of malignant melanoma cell nuclei differs significantly from the intradermal and dysplastic naevi (p ≤ 0.001, Steel-Dwass Multiple Comparison Test). Additionaly, ROC analysis confirmed the value of fractal dimension based evaluation. It is suggested that the estimation of fractal dimension from the perimeter-area relation of the cell nuclei may be a potentially useful morphometric parameter in the medical differential diagnosis of pigmented skin lesions.

Izvorni jezik
Engleski

Znanstvena područja
Fizika, Temeljne medicinske znanosti, Kliničke medicinske znanosti



POVEZANOST RADA

Projekti:
MZOS-098-0982929-2524 - Modeliranje bioaktivnih molekula i ispitivanje njihovih svojstava i učinka (Štambuk, Nikola, MZOS ) ( CroRIS)
MZOS-108-1083570-3643 - Kvantitativna analiza i prijenos slike u patologiji (Seiwerth, Sven, MZOS ) ( CroRIS)

Ustanove:
Institut "Ruđer Bošković", Zagreb,
Medicinski fakultet, Zagreb

Profili:

Avatar Url Gorana Aralica (autor)

Avatar Url Nikola Štambuk (autor)

Avatar Url Danko Milošević (autor)

Avatar Url Sven Seiwerth (autor)

Avatar Url Paško Konjevoda (autor)

Poveznice na cjeloviti tekst rada:

doi link.springer.com

Citiraj ovu publikaciju:

Aralica, Gorana; Milošević, Danko; Konjevoda, Paško; Seiwerth, Sven; Štambuk, Nikola
Estimation of fractal dimension in differential diagnosis of pigmented skin lesions // Chaos and Complex Systems : Proceedings of the 4th International Interdisciplinary Chaos Symposium / Stavrinides, Stavros ; Banerjee, Santo ; Caglar, Hikmet ; Ozer, Mehmet (ur.).
Berlin: Springer, 2013. str. 233-238 doi:10.1007/978-3-642-33914-1_30 (poster, međunarodna recenzija, cjeloviti rad (in extenso), znanstveni)
Aralica, G., Milošević, D., Konjevoda, P., Seiwerth, S. & Štambuk, N. (2013) Estimation of fractal dimension in differential diagnosis of pigmented skin lesions. U: Stavrinides, S., Banerjee, S., Caglar, H. & Ozer, M. (ur.)Chaos and Complex Systems : Proceedings of the 4th International Interdisciplinary Chaos Symposium doi:10.1007/978-3-642-33914-1_30.
@article{article, author = {Aralica, Gorana and Milo\v{s}evi\'{c}, Danko and Konjevoda, Pa\v{s}ko and Seiwerth, Sven and \v{S}tambuk, Nikola}, year = {2013}, pages = {233-238}, DOI = {10.1007/978-3-642-33914-1\_30}, keywords = {fractal, dimension, diagnosis, skin, lesions, melanoma}, doi = {10.1007/978-3-642-33914-1\_30}, isbn = {978-3-642-33914-1}, title = {Estimation of fractal dimension in differential diagnosis of pigmented skin lesions}, keyword = {fractal, dimension, diagnosis, skin, lesions, melanoma}, publisher = {Springer}, publisherplace = {Antalya, Turska} }
@article{article, author = {Aralica, Gorana and Milo\v{s}evi\'{c}, Danko and Konjevoda, Pa\v{s}ko and Seiwerth, Sven and \v{S}tambuk, Nikola}, year = {2013}, pages = {233-238}, DOI = {10.1007/978-3-642-33914-1\_30}, keywords = {fractal, dimension, diagnosis, skin, lesions, melanoma}, doi = {10.1007/978-3-642-33914-1\_30}, isbn = {978-3-642-33914-1}, title = {Estimation of fractal dimension in differential diagnosis of pigmented skin lesions}, keyword = {fractal, dimension, diagnosis, skin, lesions, melanoma}, publisher = {Springer}, publisherplace = {Antalya, Turska} }

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