Naslov
BMI as a prognostic feature in patients with breast cancer treated with chemo/endocrine therapy

Autori
Katalinic, Darko ; Santek, Fedor ; Juretic, Antonio ; Basic-Koretic, Martina ; Loncar, Kresimir ; Soce, Majana ; Nikolac, Nora ; Plestina, Stjepko

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Endocrine, Abstracts / - Kopenhagen : BioScientifica, 2013

Skup
15th European Congress of Endocrinology

Mjesto i datum
Kopenhagen, Danska, 27.04.2013. - 01.05.2013

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
BMI; breast cancer

Sažetak
Introduction: High BMI has been associated with an increased risk for breast cancer among premenopausal and postmenopausal women. Several biological mechanisms play a significant role in the genesis and progression of breast cancer. Material and methods: This study aimed to investigate relationship between BMI and breast cancer diagnosis or progression in a Croatian population. BMI, presence or absence of breast cancer and its clinical-pathological characteristics were analyzed in a series of 110 breast cancer women and compared with those of 110 healthy women prospectively. Results: BMI was significantly associated with a larger-tumour size (BMI ≥30 respect to normal weight, P=0.0047) and a higher probability of having positive axillary lymph node (P<0.0001). Conclusion: The analysis of pathological features of cancer indicates that normal weight women have a significantly higher probability of having a smaller breast cancer at time of diagnosis and negative axillary lymph nodes. BMI is an independent prognostic factor in patients with breast cancer treated with chemo/endocrine therapy in Croatian population.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA