Pregled bibliografske jedinice broj: 621288
Effects of Alpha-MSH on Corneal Epithelial Lesions in Rats
Effects of Alpha-MSH on Corneal Epithelial Lesions in Rats // Collegium antropologicum, 36 (2012), 4; 1407-1411 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 621288 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Effects of Alpha-MSH on Corneal Epithelial Lesions in Rats
Autori
Pavan, Josip ; Lukenda, Adrian ; Štambuk, Nikola ; Konjevoda, Paško ; Kaštelan, Snježana ; Ćurković, Marko.
Izvornik
Collegium antropologicum (0350-6134) 36
(2012), 4;
1407-1411
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
alpha-MSH ; cornea ; drops ; epithelization ; wound ; healing ; irritation
Sažetak
We investigated the influence of alpha-melanocyte stimulating hormone (alpha-MSH) on the healing of corneal epithelial lesions in male Wistar rats. The lesions were induced by abrading corneal epithelium with a surgical lancet under a biomicroscope. Before the abrasion corneal epithelium was softened with 40% ethanol. Alpha-MSH drops in a concentration of 1×10–4 mg/mL significantly promoted epithelial healing, when compared to the control group treated with 0.9% NaCl. Significant reduction of ocular irritation was also observed. Topical alpha-MSH medication could promote the healing of corneal wounds and reduce local inflammatory response without the major side effects of the corticosteroid therapy.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
POVEZANOST RADA
Projekti:
098-0982929-2524 - Modeliranje bioaktivnih molekula i ispitivanje njihovih svojstava i učinka (Štambuk, Nikola, MZOS ) ( CroRIS)
Ustanove:
Institut "Ruđer Bošković", Zagreb,
Klinička bolnica "Dubrava"
Profili:
Paško Konjevoda
(autor)
Snježana Kaštelan
(autor)
Josip Pavan
(autor)
Josip Pavan
(autor)
Marko Ćurković
(autor)
Nikola Štambuk
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Social Science Citation Index (SSCI)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE