Naslov
Annealing induced transformation of radicals in γ-irradiated trehalose

Autori
Šarić, Iva ; Jokić, Milan ; Rakvin, Boris ; Kveder, Marina ; Maltar-Strmečki, Nadica

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, neobjavljeni rad, znanstveni

Izvornik
The 6th EFEPR School on Advanced Electron Paramagnetic Resonance (EPR) Spectroscopy, 12-18 January, 2013, Weizman Institute of Science, Israel / - , 2013

Skup
The 6th EFEPR School on Advanced Electron Paramagnetic Resonance (EPR) Spectroscopy, 12-18 January, 2013, Weizman Institute of Science, Israel

Mjesto i datum
Reẖovot, Izrael, 12.01.2013. - 18.01.2013

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
trehaloza; radikali; EPR
(trehalose; radicals; EPR)

Sažetak
Trehalose, a non-reducing disaccharide is a matter of common interest in many research areas such as chemistry, biology, food chemistry, pharmaceutics, bioscience etc. Trehalose and other disaccharides were intensively studied due to their bio-protection effect, which refers to their ability to allow organisms to survive under extreme dehydration or freezing conditions. Though this mechanism is still unknown, many researchers believe that protection of the biomaterials and living organisms under extreme conditions is associated with amorphous characteristics of the matrices which they formed, being inversely related to the degree of crystallization. Consequently, the polymorphism of trehalose has been the subject of intense research in recent time. On the other hand, trehalose is suitable as model system for investigation of the nature and reactions of radicals induced by direct radiation effects in the deoxyribose sugar of DNA. Furthermore, understanding the behavior of radiation-induced defects in trehalose in different polymorphic forms is important for radiation dosimetry purposes4 and for the detection and characterization of irradiated final products in the pharmaceutical and food industry. Therefore, thermal stability and decay kinetics of EPR signals in γ-irradiated trehalose in different polymorphic forms were investigated using isothermal and isochronal annealing experiments.

Izvorni jezik
Engleski

Znanstvena područja
Fizika, Kemija

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