Naslov
TEM istraživanje utjecaja monomerne i dimerne površinski aktivne tvari na nastajanje amorfnog kalcijevog fosfata
(TEM study of amorphous calcium phosphate formation in the presence of monomeric and dimeric surfactants)

Autori
Selmani, Atiđa ; Milanović, Ivana ; Gajović, Andreja ; Gajović, Srečko ; Jurašin, Darija ; Dutour Sikirić, Maja

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Hrvatski mikroskopijski simpozij, Knjiga sažetaka / Gajović, A ; Tomašić, N - Zagreb : Hrvatsko mikroskopijsko društvo, 2012, 35-36

ISBN
978-953-57138-1-4

Skup
Hrvatski mikroskopijski simpozij

Mjesto i datum
Pula, Hrvatska, 16.11.2012. - 17.11.2012

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Nije recenziran

Ključne riječi
TEM; amorfni kalcijev fosfat; površinski aktivne tvari
(TEM; amorphous calcium phosphate; surfactants)

Sažetak
A major problem encountered in the application of bone bioimplant materials is their slower rate of resorption in comparison to the rate of new bone formation. It was shown that the rate of new bone formation coincides more closely with the resorption rate of poorly crystalline or amorphous calcium phosphate (ACP) cements and ceramics [1]. However, these materials still exhibit problems of mechanical strength, injectability, and application techniques. It is known that the highly hydrate spherulites of ACP grow by aggregation of much smaller primary particles and are subsequently joined together by secondary aggregation into chainlike structures [2]. Therefore coating of ACP primary particles with surfactants could be the solution to some of these problems. In recent years, dimeric surfactants, consisting of two monomeric surfactants linked by a spacer at the level of the head groups, have attracted considerable attention due to their superior properties in comparison to conventional surfactants. In this work we have compared the influence of monomeric dodecyltrimethylammonium bromide, DTAB, and corresponding dimeric dimethylene-1, 2-bis(dodecyldimethylammonium bromide), 12-2-12 (Figure 1), on the formation of ACP. Formation of ACP was followed by pH measurements and formed ACP particles were characterized by TEM and DLS. It was shown that wormlike 12-2-12 micelles excert the largest, but opposite, effect on both primary ACP nano particles and ACP secondary micro aggregates (Figure 2.).

Izvorni jezik
Hrvatski

Znanstvena područja
Kemija

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