Naslov
Microstructural characterizations of different Mn- oxide nanoparticles used as models in toxicity studies

Autori
Gotić, Marijan ; Jurkin, Tanja ; Musić, Svetozar ; Unfried, Klaus ; Sydlik, Ulrich ; Bauer-Šegvić, Anamarija

Izvornik
Journal of molecular structure (0022-2860) 1044 (2013); 248-254

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
manganese oxides; nanoparticles; microstructures; toxicity

Sažetak
Mn-oxide microstructures were investigated by XRD, FT-IR, TEM, FE SEM and EDS techniques. The oxidation of the aqueous solutions of manganese (II) chloride by hydrogen peroxide was employed to synthesize pure 20-30-nm pseudospherical hausmannite (Mn3O4) nanoparticles and manganite (γ-MnOOH) nanowires. The α-MnO2 nanotubes and nanorods were hydrothermally synthesized starting from a KMnO4 precursor, then modified with the addition of divalent metal cations Mn2+, Cu2+, Ni2+ and Fe2+. The modification with Mn2+ induced the transformation of α-MnO2 nanotube into 3D β- MnO2 (pyrolusite) prismatic nanoparticles, whereas the low-crystalline α-MnO2 nanorods were transformed into disc-like γ-MnO2 nanoparticles. The modification with Cu2+ and Ni2+ induced the structural transformation of α-MnO2 into a mixture of MnO2 polymorphs. The modification with Cu2+ decreased, whereas the modification with Ni2+ improved the crystallinity of MnO2. The modification with Fe2+ induced the structural transformation of α-MnO2 into γ-MnO2, a decrease in crystallinity and the segregation of α-Fe2O3 (hematite). Thus the modification of MnO2 with Fe2+ (Mn2+) divalent metal cations that can be oxidized into Fe3+ (Mn4+) by a KMnO4 precursor differs significantly in comparison with, in this case, non-oxidizable cations such as Cu2+ and Ni2+. On the other hand, the advantage that the modification of MnO2 with Mn2+ produces chemically identical compounds with different morphology can be used as a model system for toxicity studies. In this work the preliminary measurements of intracellular oxidative stress in epithelial cells induced by manganese oxide nanoparticles are reported.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

Napomena
EUCMOS XXXIEUCMOS XXXI ; Simion Aştilean, Austin J. Barnes, Vasile Chiş, Onuc Cozar (ur.).

POVEZANOST RADA