Naslov
Anthraquinone profile, antioxidant and antimicrobial activity of bark extracts of Rhamnus alaternus, R. fallax, R. intermedia and R. pumila

Autori
Kosalec, Ivan ; Kremer, Dario ; Locatelli, Marcello ; Epifano, Francesco ; Genovese, Salvatore ; Carlucci, Giuseppe ; Randić, Marko ; Zovko Končić, Marijana

Izvornik
Food chemistry (0308-8146) 136 (2013), 2; 335-341

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Rhamnus spp.; antioxidant; antimicrobial; anthraquinones

Sažetak
Rhamnus alaternus L., R. fallax Boiss., R. intermedia Steud. et Hochst., and R. pumila Turra from natural stands in Croatia. The most abundant anthraquinones in the investigated extracts were chrysophanol in R. alaternus (3.14 mg/g), emodin in R. pumila (0.339 mg/g), and physcion in R. fallax (2.70 mg/g) and R. intermedia (0.285 mg/g). The species exhibiting the highest antioxidant activity were R. fallax and R. pumila. A positive correlation was observed between total phenolic and flavonoid levels of the extracts and antioxidant activity in some of the assays. All species showed antimicrobial activity against Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Candida albicans, Aspergillus niger and Microsporum gypseum with minimal inhibitory concentrations equal to or below 2.500 mg/mL. The results indicate that the investigated Rhamnus species are a source of anthraquinones and other phenols, which act as multifunctional antioxidants with antimicrobial activity.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Farmacija, Šumarstvo

POVEZANOST RADA