Naslov
Acyclic analogues of purine nucleosides: one- and two-dimensional 1H and 13C NMR evidences for N-9 and N-7 regioisomers

Autori
Raić, Silvana ; Pongračić, Mario ; Vorkapić-Furač, Jasna ; Vikić-Topić, Dražen ; Mintas, Mladen

Izvornik
Spectroscopy letters (0038-7010) 29 (1996), 6; 1141-1155

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
acyclonucleosides ; purine ; adenine ; N-9 and N-7 regioisomers ; 1H NMR ; 13C NMR ; 2D homo- and heteronuclear correlation spectroscopy

Sažetak
It has been established by means of 1D and 2D 1H and 13C NMR spectroscopy that adenine acyclonucleosides are substituted at either N-9 or N-7 with 2", 3"-dihydroxyprop-1-yl (2 and 3) or 2"-hydroxyprop-1-yl (4 and 5) aliphatic chains. The N-3 isomer has not been formed, as claimed previously. This was deduced on the basis of chemical shifts, substituent induced chemical shifts, magnitude and multiplicity of C-H couplings as well as connectivities in 2D homo- and heteronuclear correlation spectra.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

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