Naslov
Assessment of perinatal mercury exposure in coastal Croatia

Autori
Jurasović, Jasna ; Lulić (Sekovanić), Ankica ; Varnai, Veda Marija ; Piasek, Martina ; Matek Sarić, Marijana

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstracts of the 48th Congress of the European Societies of Toxicology, EUROTOX 2012 ; u: Toxicology Letters 211 (2012) (S1) / - : Elsevier, 2012, S146-S147

Skup
EUROTOX 2012, 48th Congress of the European Societies of Toxicology "Safety Science Serving Society"

Mjesto i datum
Stockholm, Švedska, 17.06.2012. - 20.06.2012

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
fish intake; methylmercury; maternal blood; perinatal exposure; umbilical cord blood

Sažetak
Mercury is an environmental contaminant. It is present in fish and seafood mostly in the form of methylmercury, a highly toxic compound that could cause nerodevelopmental disorders with lifelong disability. Placenta does not act as a barrier to methylmercury and it easily passes to unborn child. We assessed perinatal exposure to mercury in 101 healthy postpartum women (aged 29±4.7 years) who gave birth at term by vaginal delivery during 2010 in General Hospital of Zadar County, coastal Croatia. Personal information, collected by a questionnaire, included data on dietary fish and seafood consumption and number of amalgam fillings. Maternal venous blood and umbilical cord blood samples were taken after delivery. Total mercury concentration (T-Hg) was determined in blood and serum using ICP-MS method. Results. Median and range of T-Hg were 1.83 (0.18-25.3) and 3.11 (0.10-46.9) μg/L in maternal blood and umbilical cord blood and 0.62 (0.10-4.59) and 0.44 (0.05-4.03) μg/L in maternal serum and umbilical cord serum. T-Hg in maternal and umbilical cord blood was associated with weakly fish consumption (p<10-7) and maternal age (p<0.02) and T-Hg in maternal and umbilical cord serum was associated with both fish consumption (p<10-4) and number of dental amalgam fillings (p<0.04). Multiple regression model (adjusted for maternal age and smoking habit) confirmed Pearson’s correlation results. Values of T-Hg in maternal and cord blood and serum were mainly related to maternal dietary fish intake. These values are higher than T-Hg determined in continental parts of Europe and lower than in certain other Mediterranean areas.

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita, Prehrambena tehnologija

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