Naslov
Gizzerosine Induced Histoopathological Lesions in Broiler Chicks

Autori
Tišljar, Marina ; Grabarević, Željko ; Artuković, Branka ; Šimec, Zoran ; Džaja, Petar ; Herak-Perković, Vlasta

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
10th "Ljudevit Jurak" International Symposium on comparative Pathology / Talan-Hranilović, Jasna ; Krušlin, Božo - Zagreb, 1999

Skup
10th "Ljudevit Jurak" International Symposium on comparative Pathology

Mjesto i datum
Zagreb, Hrvatska, 04.06.1999. - 05.06.1999

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
gizzerosine; broiler chicks

Sažetak
Gizzerosine is a well-known toxic substance spontaneously produced during the heating process of fish meal. Because of its action on H2-receptors of histamine it stimulates gastric juice secretion and induces gizzard erosions (GE) (Okazaki et al., 1983; Masumura et al., 1985). Its pathological effects on other organs have not yet been described. In this work the pathological effects of gizzerosine on different chicken organs were investigated. The ROSS broiler chicks were divided into three groups: group A received 100% of non-medicated commercial mash for broiler chicks. For group B 50% of commercial mash was replaced with unheated fish meal (0.5 ppm gizzerosine) and in group C with heated fish meal (1.15 ppm gizzerosine) during an experimental 7-day period. Fourteen chicks from each group were sacrificed every day during one week. Necropsy did not reveal notable differences between treated groups. Samples of gastrointestinal, cardiovascular and lymphoid organs, of brain and kidney were collected for histopathological analysis; fixed in 10% formalin solution, embedded in paraffin, sections of 5 ?m thickness were cut on a microtome and stained with hematoxilyn-eosin stain. Histopathological findings predominantly developed in gastrointestinal organs (proventricular mucosal degeneration; intestinal mucosal and submucosal edema with/without multiple vacuoles; proventricular and intestinal submucosal fibroplasia; gizzard cuticle erosions). The most prominent were intestinal lesions; their severity increased towards the end of the trial, especially in group C. References Okazaki et al ., 1983; Agric. Biol. Chem. 47: 2949. Masumura et al., 1985; Poult. Sci. 64: 356

Izvorni jezik
Engleski

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