Pregled bibliografske jedinice broj: 590470
Synthesis of N-1-sulfonyl-5-(1, 2, 3-triazol-4-yl)uracil Derivatives and Evaluation of Their Anticancer Activity
Synthesis of N-1-sulfonyl-5-(1, 2, 3-triazol-4-yl)uracil Derivatives and Evaluation of Their Anticancer Activity // Book of abstracts : XX. International Roundtable on Nucleosides Nucleotides and Nucleic Acids
Montréal, 2012. str. 46-46 (poster, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 590470 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Synthesis of N-1-sulfonyl-5-(1, 2, 3-triazol-4-yl)uracil Derivatives and Evaluation of Their Anticancer Activity
Autori
Saftić, Dijana ; Glavaš-Obrovac, Ljubica ; Žinić, Biserka
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
Book of abstracts : XX. International Roundtable on Nucleosides Nucleotides and Nucleic Acids
/ - Montréal, 2012, 46-46
Skup
XX. International Roundtable on Nucleosides Nucleotides and Nucleic Acids
Mjesto i datum
Montréal, Kanada, 05.08.2012. - 09.08.2012
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
Triazolni derivati uracila
(Triazole Derivatives of Uracil)
Sažetak
New 1, 4-disubstituted-1, 2, 3-triazoles were synthesized from corresponding alkyl halides, sodium azide and 5-ethynyluracil via a copper(I) catalyzed three-component reaction. The synthesis of N-1-sulfonyl-5-(1, 2, 3-triazol-4-yl)uracil derivatives was accomplished in the condensa-tion reaction with sulfonyl chlorides in the presence of DBU in DMF. Obtained derivatives were tested for their cytostatic activity.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
POVEZANOST RADA
Projekti:
098-0982914-2935 - Sinteza novih biološki aktivnih derivata nukleobaza i nukleotida (Žinić, Biserka, MZOS ) ( CroRIS)
Ustanove:
Institut "Ruđer Bošković", Zagreb
