Naslov
Method for real time tumour visualisation and demarcation by means of photodynamic diagnosis

Autori
Kopriva, Ivica

Broj patenta
US8, 224, 427

Godina
2012

Datum patenta
17. 7. 2012.

Nositelj prava
Nixon Peabody, LLP, 401 9th Street N.W., Suite 900, Washington, DC 20004-2128, US, Zagreb, Hrvatska

Sažetak
Proposed invention is related to the field of photodynamic therapy and photodiagnosis. Specifically, a new algorithm is presented for visualisation and spatial demarcation of various types of tumours and unhealthy tissue through unsupervised segmentation of the fluorescent multispectral image. Image is acquired through recording of the emission of the tissue illuminated by the light that induces fluorescence in the tumour. For this purpose tissue is treated by photo sensitizer. Algorithm for real time visualisation and spatial demarcation of the tumour by means of the analysis of fluorescent image consists of the recording of the fluorescent image (1) that represents linear combination of the unknown classes S by multispectral camera, transformation of the fluorescent multispectral image into new multispectral image (2) applying nonlinear dimensionality expansion, linear transformation of the multispectral image (2) with extended dimensionality, independent component analysis of the innovation representations of the multispectral image (3) that is result of the transformation of the fluorescent image (1) and multispectral image (2), extraction o the tumour map or class of interest in accordance with the chosen criterion and visualisation of tumour on monitor.

Izvorni jezik
Engleski

Znanstvena područja
Matematika, Računarstvo, Kliničke medicinske znanosti

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