Pregled bibliografske jedinice broj: 588648
Platelet serotonin in primary Sjögren's syndrome: Level and relation with disease activity
Platelet serotonin in primary Sjögren's syndrome: Level and relation with disease activity // Journal of neuroimmunology, 251 (2012), 1/2; 87-89 doi:10.1016/j.jneuroim.2012.06.011 (međunarodna recenzija, članak, znanstveni)
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Naslov
Platelet serotonin in primary Sjögren's syndrome:
Level and relation with disease activity
Autori
Šarac, Helena ; Markeljević, Jasenka ; Mokrović, Gordana ; Erdeljić, Viktorija ; Božina, Nada ; Čičin- Šain, Lipa
Izvornik
Journal of neuroimmunology (0165-5728) 251
(2012), 1/2;
87-89
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
platelet serotonin ; Sjögren's syndrome ; ESSDAI
Sažetak
Primary Sjögren's syndrome (pSS) is chronic autoimmune disorder of unknown ethiopathogenesis. In line with the concept of neuroimmunohormonal dysregulation in inflammatory rheumatic diseases, the aim of this study was to investigate platelet serotonin level (PSL) in patients with pSS and its relation with the activity and duration of the disease. Significantly lower PSL in pSS patients (N=61) was shown as compared to healthy controls (N=103). No correlation was found between PSL and the actual disease activity assessed by the recently developed EULAR Sjögren's Syndrome Disease Activity Index (ESSDAI). Results suggest involvement of the serotonin system in the pathogenesis of pSS.
Izvorni jezik
Engleski
Znanstvena područja
Biologija, Temeljne medicinske znanosti, Kliničke medicinske znanosti
POVEZANOST RADA
Projekti:
MZOS-098-1081870-2397 - Serotonergični mehanizmi u alkoholizmu (Čičin-Šain, Lipa, MZOS ) ( CroRIS)
MZOS-108-1081874-2416 - Sjögrenov sindrom - neurohumoralna regulacija autoimunosti i aterogeneza (Markeljević, Jasenka, MZOS ) ( CroRIS)
Ustanove:
Institut "Ruđer Bošković", Zagreb,
Medicinski fakultet, Zagreb,
KBC "Sestre Milosrdnice",
Klinički bolnički centar Zagreb
Profili:
Jasenka Markeljević
(autor)
Helena Šarac
(autor)
Nada Božina
(autor)
Lipa Čičin-Šain
(autor)
Gordana Mokrović
(autor)
Poveznice na cjeloviti tekst rada:
Pristup cjelovitom tekstu rada doi www.sciencedirect.com dx.doi.orgCitiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE