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Pregled bibliografske jedinice broj: 582354

Remarkably fast and selective aromatization of Hantzsch esters with MoOCl4 and MoCl5: A chemical model for possible biologically relevant properties of molybdenum-containing enzymes

Litvić, Mladen; Regović, Maja; Šmic, Karolina; Lovrić, Marija; Filipan-Litvić, Mirela
Remarkably fast and selective aromatization of Hantzsch esters with MoOCl4 and MoCl5: A chemical model for possible biologically relevant properties of molybdenum-containing enzymes // Bioorganic & medicinal chemistry letters, 22 (2012), 11; 3676-3681 doi:10.1016/j.bmcl.2012.04.043 (međunarodna recenzija, članak, znanstveni)

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Naslov
Remarkably fast and selective aromatization of Hantzsch esters with MoOCl4 and MoCl5: A chemical model for possible biologically relevant properties of molybdenum-containing enzymes

Autori
Litvić, Mladen ; Regović, Maja ; Šmic, Karolina ; Lovrić, Marija ; Filipan-Litvić, Mirela

Izvornik
Bioorganic & medicinal chemistry letters (0960-894X) 22 (2012), 11; 3676-3681

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
1; 4-Dihydropyridines; Aromatization; Dealkylation; Molybdenum pentachloride; Molybdenum oxytetrachloride

Sažetak
Mo(VI) and Mo(V) salts both react selectively with Hantzsch esters to produce substitute pyridines in good-to-excellent yield (75–99%). The remarkable reactivity and selectivity of MoOCl4 under reflux of acetonitrile and MoCl5 in dichloromethane at room temperature encouraged us to propose that molybdenum- containing enzymes (such as xanthine or aldehyde oxidase) also participate to some degree in the metabolism of 1, 4-dihydropyridine drugs in the liver analogous to NADH in the respiratory chain.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA

Profili:

Avatar Url Mladen Litvić (autor)

Avatar Url Mirela Filipan-Litvić (autor)

Avatar Url Marija Lovrić (autor)

Poveznice na cjeloviti tekst rada:

Pristup cjelovitom tekstu rada doi ac.els-cdn.com www.sciencedirect.com dx.doi.org

Citiraj ovu publikaciju:

Litvić, Mladen; Regović, Maja; Šmic, Karolina; Lovrić, Marija; Filipan-Litvić, Mirela
Remarkably fast and selective aromatization of Hantzsch esters with MoOCl4 and MoCl5: A chemical model for possible biologically relevant properties of molybdenum-containing enzymes // Bioorganic & medicinal chemistry letters, 22 (2012), 11; 3676-3681 doi:10.1016/j.bmcl.2012.04.043 (međunarodna recenzija, članak, znanstveni)
Litvić, M., Regović, M., Šmic, K., Lovrić, M. & Filipan-Litvić, M. (2012) Remarkably fast and selective aromatization of Hantzsch esters with MoOCl4 and MoCl5: A chemical model for possible biologically relevant properties of molybdenum-containing enzymes. Bioorganic & medicinal chemistry letters, 22 (11), 3676-3681 doi:10.1016/j.bmcl.2012.04.043.
@article{article, author = {Litvi\'{c}, Mladen and Regovi\'{c}, Maja and \v{S}mic, Karolina and Lovri\'{c}, Marija and Filipan-Litvi\'{c}, Mirela}, year = {2012}, pages = {3676-3681}, DOI = {10.1016/j.bmcl.2012.04.043}, keywords = {1, 4-Dihydropyridines, Aromatization, Dealkylation, Molybdenum pentachloride, Molybdenum oxytetrachloride}, journal = {Bioorganic and medicinal chemistry letters}, doi = {10.1016/j.bmcl.2012.04.043}, volume = {22}, number = {11}, issn = {0960-894X}, title = {Remarkably fast and selective aromatization of Hantzsch esters with MoOCl4 and MoCl5: A chemical model for possible biologically relevant properties of molybdenum-containing enzymes}, keyword = {1, 4-Dihydropyridines, Aromatization, Dealkylation, Molybdenum pentachloride, Molybdenum oxytetrachloride} }
@article{article, author = {Litvi\'{c}, Mladen and Regovi\'{c}, Maja and \v{S}mic, Karolina and Lovri\'{c}, Marija and Filipan-Litvi\'{c}, Mirela}, year = {2012}, pages = {3676-3681}, DOI = {10.1016/j.bmcl.2012.04.043}, keywords = {1, 4-Dihydropyridines, Aromatization, Dealkylation, Molybdenum pentachloride, Molybdenum oxytetrachloride}, journal = {Bioorganic and medicinal chemistry letters}, doi = {10.1016/j.bmcl.2012.04.043}, volume = {22}, number = {11}, issn = {0960-894X}, title = {Remarkably fast and selective aromatization of Hantzsch esters with MoOCl4 and MoCl5: A chemical model for possible biologically relevant properties of molybdenum-containing enzymes}, keyword = {1, 4-Dihydropyridines, Aromatization, Dealkylation, Molybdenum pentachloride, Molybdenum oxytetrachloride} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE

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