Naslov
Campanula portenschlagiana Roem. et Schult. : Chemical and Antimicrobial Activities
(Campanula portenschlagiana Roem. et Schult . : Chemical and Antimicrobial Activities)

Autori
Politeo, Olivera ; Skočibušić, Mirjana ; Burcul, Franko ; Maravić, Ana ; Carev, Ivana ; Ruščić, Mirko ; Miloš, Mladen

Izvornik
Chemistry & biodiversity (1612-1872) 10 (2013), 6; 1072-1080

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Campanula portenschlagiana; Essential Oils; Antimicrobial activity; Extended-spectrum b-lactamase (ESBL)

Sažetak
The phytochemical profile and the antimicrobial effects of the volatile oil and the aqueous extract of Campanula portenschlagiana, a wild growing plant endemic to Croatia, were described. In the volatile oil, 53 compounds were identified by GC-FID and GC/MS analyses. Diterpene alcohols constituted the major compound class with labda-13(16), 14-dien-8-ol as the main compound. The aqueous extract was characterized by the total phenolic content. The antimicrobial potential of the volatile oil and the aqueous extract was evaluated against a diverse range of microorganisms comprising food-spoilage and food-borne pathogens. The volatile oil exhibited interesting and promising antimicrobial effects against the tested species, which were generally more pronounced against Gram-negative bacteria. In addition, the inhibitory effect of this volatile oil was also evaluated against eleven extended-spectrum b-lactamase (ESBL)-producing isolates. The results suggest that the C. portenschlagiana volatile oil might be used as antimicrobial agent against ESBL-producing isolates and Gram-negative bacteria.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biologija

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