Pregled bibliografske jedinice broj: 579
Chronic lead poisoning, renal function and immune response
Chronic lead poisoning, renal function and immune response // Arhiv za higijenu rada i toksikologiju = Archives of industrial hygiene and toxicology, 47 (1996), 1; 1-8 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 579 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Chronic lead poisoning, renal function and immune response
Autori
Restek-Samaržija, Nada ; Momčilović Berislav ; Trošić, Ivančica ; Piasek, Martina ; Samaržija, Miroslav
Izvornik
Arhiv za higijenu rada i toksikologiju = Archives of industrial hygiene and toxicology (0004-1254) 47
(1996), 1;
1-8
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
alimentary exposure; B-lymphocytes; creatinine clearance; DTPA clearance; kidney; occupational exposure; T- lymphocytes
Sažetak
The aim of this study was to investigate possible correlations between chronic, recurrent lead poisoning, renal function and immune response. The study involved 74 patients with a history of at least one lead poisoning. Fifty-three patients were occupationally poisoned, and 21 were poisoned accidentally after consumption of alcohol beverages or food from lead glazed pottery. In all patients glomerular filtration rate (GFR) was determined by measuring creatinine and DTPA clearances, and T- and B-lymphocytes were assessed as indicators of cellular and humoral immunity. A significant negative correlation was found between the number of past lead poisonings indicating increased lead body burden, and both creatinine and DTPA clearances. There was a significant positive correlation between the number of poisonings and the percentage of B-lymphocytes (r = 0.31 ; P < 0.05), and no correlation at all with the T-lymphocyte count. Our results show that chronic, recurrent lead poisoning with a consequently increasing lead body burden can cause an impairment in renal function and a concomitant stimulation of humoral immunity.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti, Javno zdravstvo i zdravstvena zaštita
POVEZANOST RADA
Ustanove:
Institut za medicinska istraživanja i medicinu rada, Zagreb
Profili:
Ivančica Trošić
(autor)
Nada Restek-Samaržija
(autor)
Miroslav Samaržija
(autor)
Berislav Momčilović
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Scopus
- MEDLINE
Uključenost u ostale bibliografske baze podataka::
- Biological Abstracts
- Chemical Abstracts
- Elsevier BIOBASE
- Excerpta Medica/EMBASE
- Index Medicus
- MEDLINE
- Industrial Hygiene Digest
- Toxicology Abstracts
- TOXLINE
- etc.