Naslov
Promjene tjelesne težine kod bolesnika s kroničnim bubrežnim zatajenjem na početku liječenja hemodijalizom
(Body weight changes in patients with chronic renal failure starting hemodialysis treatment)

Autori
Živčić-Ćosić, Stela ; Matić-Glažar, Đurđica ; Legac, Igor ; Čohar, Franjo

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Periodicum biologorum / - , 2000, 127-127

Skup
2. Hrvatski kongres nefrologije, dijalize i transplantacije

Mjesto i datum
Dubrovnik, Hrvatska, 21.10.1998. - 25.10.1998

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Domaća recenzija

Ključne riječi
tjelesna težina; kronično bubrežno zatajenje; hemodijaliza
(body weight; chronic renal failure; hemodialysis)

Sažetak
Background and purpose: Cardiovascular complications are the presenting cause of death in over one half of dialytic patients. Therefore hypertension has to be treated adequately, with correction of overhydration and the achievement of dry weight after the initiation of hemodialysis being the first step in its treatment. The resulting changes in patient´s body weight, their influence on blood pressure and signs of hypervolemia on chest radiographs were analyzed. Methods: In 37 patients with terminal renal failure, changes in body weight and blood pressures were registered through the first three months of hemodialysis treatment. Regular antihypertensive medication was discontinued and the excess body water gradually reduced to "dry" weight by means of controlled ultrafiltration on bicarbonate hemodialysis. Signs of hypervolemia were analyzed on chest radiographs, taken at the beginning and the end of the observation period. Results: After three months body weights changes ranged from -13 to +2, 5 kg (-19% to +3, 6% of initial body weight). Maximal reduction was registered with patients having chronic glomerulonephritis and diabetic nephropathy. Changes in body weight and blood pressure correlated significantly in all primary renal diseases except hypertensive vascular kidney damage (r=0.52, p<0.01). At the beginning 28 patients (76%) were hypertensive. Normotension was achieved mostly in patients having tubulointerstitial diseases (75%), and four of these patients even showed disappearance of radiographic signs of left ventricular hypertrophy. There was a significant correlation between changes in body weight and cardiothoracic index (r=0.42, p<0.01). Conclusions: Excess body water accumulated to the greatest extent in patients with terminal renal failure resulting from chronic glomerulonephritis and diabetic nephropathy. The significant correlation between the reduction in body weight and blood pressure pointed to the mainly volume-sensitive nature of hypertension. The most significant changes among measured parameters on chest radiography were observed in the cardiothoracic index.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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