Naslov
The Effects of Hyaluronic Acid, Calcium Hydroxide, and Dentin Adhesive on Rat Odontoblasts and Fibroblasts.

Autori
Bogović, Ana ; Nižetić, Jana ; Galić, Nada ; Želježić, Davor ; Micek, Vedran ; Mladinić, Marin

Izvornik
Arhiv za higijenu rada i toksikologiju (0004-1254) 62 (2011), 2; 155-161

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, kratko priopcenje, znanstveni

Ključne riječi
direct pulp capping; fibroblast proliferation; odontoblastic proliferation

Sažetak
The aim of this study was to investigate the effects and effi ciency of pulp capping preparations based on hyaluronic acid, calcium hydroxide, and dentin adhesive on the pulp tissue of Sprague-Dawley rats. The rats were killed and extracted teeth sectioned transversely through the pulp. The slices were placed in a rpmI 1640 cell culture medium supplemented with 10 % foetal calf serum. During 14 days of cultivation cultures were treated with preparations that contained hyaluronic acid (Gengigel Prof®), and calcium hydroxide (ApexCal®), or with dentin adhesive (Excite®). Cellularity and viability of fi broblasts and odontoblasts was analysed using a haemocytometer. Hyaluronic acid proved most effi cient and the least toxic for direct pulp capping. Even though calcium hydroxide and dentin adhesive demonstrated a higher degree of cytotoxicity, their effects were still acceptable in terms of biocompatibility.

Izvorni jezik
Engleski

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