Naslov
Spectroscopic studies of methimazole reactivity in aqueous solutions

Autori
Cvijanović, Danijela ; Damjanović, Vladimir ; Lovrić, Jasna ; Picek, Igor ; Foretić, Blaženka

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
14th European Conference on the Spectroscopy of Biological Molecules ; Book of Abstracts / - , 2011

Skup
14th European Conference on the Spectroscopy of Biological Molecules

Mjesto i datum
Coimbra, Portugal, 29.08.2011. - 03.09.2011

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
2-mercapto-1-methylimidazole; pentacyanoferrate(II) complex; spectroscopy

Sažetak
The reactions and coordination ability of S, N-containing heterocyclic ligands such as methimazole (MMI=2-mercapto-1-methylimidazole) have been of considerable interest both from structural point of view and pharmacological importance of MMI. This study has been undertaken to investigate the mode of coordination of MMI to the pentacyanoferrate(II) moiety known as a selective probe for binding one specific group of ambidentate ligands to iron(II). Predominance of reactive tautomeric MMI isomer in aqueous solutions (pH 2-11) is determined and the stability of the formed complexes is discussed and correlated with the iron-ligand bond type and the electronic properties of the ligand. The experimental data were obtained by means of NMR and UV/Vis spectroscopy.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

POVEZANOST RADA