Naslov
Paving the way for personalised behaviourally based prevention of obesity: systematic search of the literature

Autori
Fišter, Kristina ; Vuletić, Silvije ; Kern, Josipa

Izvornik
COLLEGIUM ANTROPOLOGICUM (0350-6134) 36 (2012), S1; 201-210

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
obesity; genomics; single nucleotide polymorphism; health behaviour; public health; translational research

Sažetak
We have identified in the literature variants in 64 genes that may be involved in gene-obesity-behaviour interactions. Personalisation of behaviourally based preventive approaches against obesity seems feasible, however obesity genomics is still in the discovery phase of translational research and abundant replication studies are needed before these largely pioneering findings can be extended to practice and population impact. Automation of search algorithms and development of more efficient tools for knowledge synthesis of genomic research into gene-obesity-behaviour interactions might facilitate the advent of widely available personalised prevention approaches. Our future efforts shall therefore concentrate on developing such tools, as well as a research repository dedicated to the use of public health genomics for obesity control.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA