Large volume leukapheresis : Efficacy and safety of processing patient's total blood volume six times

Bojanić, Ines; Dubravčić, Klara; Batinić, Drago; Golubić Čepulić, Branka; Mazić, Sanja; Hren, Darko; Nemet, Damir; Labar, Boris

doi:10.1016/j.transci.2011.01.005

Pregled bibliografske jedinice broj: 545851

Large volume leukapheresis : Efficacy and safety of processing patient's total blood volume six times

Bojanić, Ines; Dubravčić, Klara; Batinić, Drago; Golubić Čepulić, Branka; Mazić, Sanja; Hren, Darko; Nemet, Damir; Labar, Boris

Large volume leukapheresis : Efficacy and safety of processing patient's total blood volume six times // Transfusion and apheresis science, 44 (2011), 2; 139-147 doi:10.1016/j.transci.2011.01.005 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 545851 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Large volume leukapheresis : Efficacy and safety of processing patient's total blood volume six times

Autori
Bojanić, Ines ; Dubravčić, Klara ; Batinić, Drago ; Golubić Čepulić, Branka ; Mazić, Sanja ; Hren, Darko ; Nemet, Damir ; Labar, Boris

Izvornik
Transfusion and apheresis science (1473-0502) 44 (2011), 2; 139-147

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
large volume ; leukapheresis ; CD34+ cell

Sažetak
Large-volume leukapheresis (LVL) differs from standard leukapheresis by increased blood flow and an altered anticoagulation regimen. An open issue is to what degree a further increase in processed blood volume is reasonable in terms of higher yields and safety. In 30 LVL performed in patients with hematologic malignancies, 6 total blood volumes were processed. LVL resulted in a higher CD34+ cell yield without a change in graft quality. Although a marked platelet decrease can be expected, LVL is safe and can be recommended as the standard procedure for patients who mobilize low numbers of CD34+ cells and when high number of CD34+ cells are required.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA

Projekti:
MZOS-108-1081872-1913 - LEUKEMIJE I TRANSPLANTACIJA KRVOTVORNIH MATIČNIH STANICA (Duraković, Nadira, MZOS ) ( CroRIS)
MZOS-108-1081872-2061 - LIMFOPROLIFERATIVNE BOLESTI I TRANSPLANTACIJA KRVOTVORNIH MATIČNIH STANICA (Nemet, Damir, MZOS ) ( CroRIS)
MZOS-214-1081347-0355 - Uloga PI3K/Akt i MAPK u regulaciji kemorezistencije leukemijskih stanica (Batinić, Drago, MZOS ) ( CroRIS)

Ustanove:
Klinički bolnički centar Zagreb,
Sveučilište Libertas

Profili:

Branka Golubić Ćepulić (autor)