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Pregled bibliografske jedinice broj: 542666

Adamantane-substituted Guanylhydrazones : Novel Inhibitors of Butyrylcholinesterase

Šekutor, Marina; Mlinarić-Majerski, Kata; Hrenar, Tomica; Tomić-Pisarović, Srđanka; Primožič, Ines
Adamantane-substituted Guanylhydrazones : Novel Inhibitors of Butyrylcholinesterase // Bioorganic chemistry, 41-42 (2012), 28-34 doi:10.1016/j.bioorg.2012.01.004 (međunarodna recenzija, članak, znanstveni)

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Naslov
Adamantane-substituted Guanylhydrazones : Novel Inhibitors of Butyrylcholinesterase

Autori
Šekutor, Marina ; Mlinarić-Majerski, Kata ; Hrenar, Tomica ; Tomić-Pisarović, Srđanka ; Primožič, Ines

Izvornik
Bioorganic chemistry (0045-2068) 41-42 (2012); 28-34

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
adamantane-substituted guanylhydrazones ; inhibitors ; butyrylcholinesterase ; kinetic and docking studies

Sažetak
A series of novel adamantane-substituted guanylhydrazones was synthesized and used in a study of inhibitory potential toward butyrylcholinesterase. The inhibition constants were determined and docking studies performed to examine the behavior of the inhibitors within the active site regions of the enzyme. The strongest interaction observed in complexes obtained by docking studies were numerous H-bonds of the guanidine group.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA

Projekti:
098-0982933-2911 - Kavezasti spojevi: ugradbene jedinice u molekularnim sustavima (Majerski, Kata, MZOS ) ( CroRIS)
119-1191344-3121 - Sinteze i enzimske transformacije biološki aktivnih spojeva (Tomić-Pisarović, Srđanka, MZOS ) ( CroRIS)

Ustanove:
Institut "Ruđer Bošković", Zagreb,
Prirodoslovno-matematički fakultet, Zagreb

Profili:

Avatar Url Kata Majerski (autor)

Avatar Url Ines Primožič (autor)

Avatar Url Srđanka Tomić-Pisarović (autor)

Avatar Url Marina Šekutor (autor)

Avatar Url Tomica Hrenar (autor)

Poveznice na cjeloviti tekst rada:

doi dx.doi.org www.sciencedirect.com

Citiraj ovu publikaciju:

Šekutor, Marina; Mlinarić-Majerski, Kata; Hrenar, Tomica; Tomić-Pisarović, Srđanka; Primožič, Ines
Adamantane-substituted Guanylhydrazones : Novel Inhibitors of Butyrylcholinesterase // Bioorganic chemistry, 41-42 (2012), 28-34 doi:10.1016/j.bioorg.2012.01.004 (međunarodna recenzija, članak, znanstveni)
Šekutor, M., Mlinarić-Majerski, K., Hrenar, T., Tomić-Pisarović, S. & Primožič, I. (2012) Adamantane-substituted Guanylhydrazones : Novel Inhibitors of Butyrylcholinesterase. Bioorganic chemistry, 41-42, 28-34 doi:10.1016/j.bioorg.2012.01.004.
@article{article, author = {\v{S}ekutor, Marina and Mlinari\'{c}-Majerski, Kata and Hrenar, Tomica and Tomi\'{c}-Pisarovi\'{c}, Sr\djanka and Primo\v{z}i\v{c}, Ines}, year = {2012}, pages = {28-34}, DOI = {10.1016/j.bioorg.2012.01.004}, keywords = {adamantane-substituted guanylhydrazones, inhibitors, butyrylcholinesterase, kinetic and docking studies}, journal = {Bioorganic chemistry}, doi = {10.1016/j.bioorg.2012.01.004}, volume = {41-42}, issn = {0045-2068}, title = {Adamantane-substituted Guanylhydrazones : Novel Inhibitors of Butyrylcholinesterase}, keyword = {adamantane-substituted guanylhydrazones, inhibitors, butyrylcholinesterase, kinetic and docking studies} }
@article{article, author = {\v{S}ekutor, Marina and Mlinari\'{c}-Majerski, Kata and Hrenar, Tomica and Tomi\'{c}-Pisarovi\'{c}, Sr\djanka and Primo\v{z}i\v{c}, Ines}, year = {2012}, pages = {28-34}, DOI = {10.1016/j.bioorg.2012.01.004}, keywords = {adamantane-substituted guanylhydrazones, inhibitors, butyrylcholinesterase, kinetic and docking studies}, journal = {Bioorganic chemistry}, doi = {10.1016/j.bioorg.2012.01.004}, volume = {41-42}, issn = {0045-2068}, title = {Adamantane-substituted Guanylhydrazones : Novel Inhibitors of Butyrylcholinesterase}, keyword = {adamantane-substituted guanylhydrazones, inhibitors, butyrylcholinesterase, kinetic and docking studies} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE

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