Naslov
Antiaggregatory Effect Of Flavonoids

Autori
Medić-Šarić, Marica ; Bojić, Mirza

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Macedonian Pharmaceutical Bulletin 57 (suppl), 2011: 5th Congress of Pharmacy in Macedonia with International Participation / Goracinova, Katerina ; Trajkovic Jolevska, Suzana - Skopje : Macedonian Pharmaceutical Society, 2011, 180-181

Skup
5th Congress of Pharmacy of Macedonia with International Participation

Mjesto i datum
Ohrid, Sjeverna Makedonija, 21.09.2011. - 25.09.2011

Vrsta sudjelovanja
Pozvano predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
platelet aggregation; flavonoids

Sažetak
Introduction Leading causes of death in developed countries are cardiovascular diseases. Polyphenols, namely flavonoids and phenolic acids, have many pharmacological properties that can explain their protective role in the prevention of cardiovascular diseases: antioxidant capacity, vasorelaxation, anti-inflammatory and antiaggregatory effects. Beneficial effects of natural sources of polyphenolics on platelet aggregation such as wine (French paradox), green tea (Asian paradox), dark chocolate, gingko, propolis are well documented. [1, 2] Although antiaggregatory activity of flavonoids is well known property of these compounds, the results of a systematic search for highly potent members of this family are still missing. Conclusion Flavonoids can effect platelet aggregation in concentrations that can be achieved in every day diet. As flavonoids are widely distributed in plant kingdom, diet should be taken into account when interpreting platelet aggregation and coagulation results.

Izvorni jezik
Engleski

Znanstvena područja
Farmacija

POVEZANOST RADA