Pregled bibliografske jedinice broj: 526884
Lewis acid promoted diastereoselective Mannich reaction of beta-lactam - tethered aldimines with 1-methoxy-1-trimethylsilyloxy-2, 2-dimethylethene
Lewis acid promoted diastereoselective Mannich reaction of beta-lactam - tethered aldimines with 1-methoxy-1-trimethylsilyloxy-2, 2-dimethylethene // ASMC, St. Petersburg ; International Symposium on Advances in Synthetic and Medicinal Chemistry / Nicolaou, K.C., Wood, Anthony (ur.).
Sankt Peterburg: LD Organisation sprl, 2011. str. 156-156 (poster, međunarodna recenzija, sažetak, ostalo)
CROSBI ID: 526884 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Lewis acid promoted diastereoselective Mannich reaction of beta-lactam - tethered aldimines with 1-methoxy-1-trimethylsilyloxy-2, 2-dimethylethene
Autori
Habuš, Ivan ; Vazdar, Katarina ; Margetić, Davor
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo
Izvornik
ASMC, St. Petersburg ; International Symposium on Advances in Synthetic and Medicinal Chemistry
/ Nicolaou, K.C., Wood, Anthony - Sankt Peterburg : LD Organisation sprl, 2011, 156-156
Skup
International Symposium on Advances in Synthetic and Medicinal Chemistry
Mjesto i datum
Sankt Peterburg, Ruska Federacija, 21.08.2011. - 25.08.2011
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
beta-lactam; Lewis acid; Mannich reaction
Sažetak
Lewis acid (ZnI2) - promoted Mannich reaction of azetidin-2-one - tethered aldimines 3a-r with silylenol ether 4 in toluene at -20 oC afforded a diastereomeric mixture of beta-amino acid esters 5a-r/6a-r. The effect of the ammount of zinc(II) iodide, temperature and a variety of groups on azetidin-2-one - tethered imines 3a-r (R1=phenyl, ferrocenyl ; R2=alkyl, aryl, ferrocenyl)on the chemical yield and the product stereoisomeric ratio was studied.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
POVEZANOST RADA
Projekti:
098-0982915-2948 - Amino-beta-laktami - intermedijari u sintezi biološki interesantnih spojeva (Tomašić, Vlasta, MZOS ) ( CroRIS)
098-0982933-3218 - Host-guest međudjelovanja u policikličkim sustavima (Margetić, Davor, MZOS ) ( CroRIS)
Ustanove:
Institut "Ruđer Bošković", Zagreb
