Naslov
Recent advances in the pathogenesis of CMV infection

Autori
Jonjić, Stipan

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, neobjavljeni rad, znanstveni

Izvornik
Final Programme of the 21st ECCMID/27th ICC 20117 / ECCMID/ICC - Milano : ECCMID/ICC, 2011, 76-76

Skup
European Congress of Clinical Microbiology and Infectuous Diseases, Milano

Mjesto i datum
Milano, Italija, 07.05.2011. - 10.05.2011

Vrsta sudjelovanja
Pozvano predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
NKG2D; MCMV; CMV vaccine; viral vaccine vector

Sažetak
The lecture included two parts: in the first part the recent discoveries in immunobiology and immunology of CMV infection were presented with emphasis on the congenital viral infection of CNS. The second part of the talk was dedicated to CMV vaccines with emphasis on MCMV expressing NKG2D ligand as a novel approach for CMV vaccine and viral vaccine vector. The presented data demonstrated that the virus expressing NKG2D ligand was strongly attenuated in vivo, but nevertheless induces potent CD8 response which is similar to one induced by WT MCMV. Most of the presented results have recently been published in JCI (Slavuljica et al)

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA