Naslov
Informed consent competency of persons with Alzheimer's dementia

Autori
Kalinić, Dubravka ; Mimica, Ninoslav

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Neurologia Croatica (2010) 59 (Suppl. 2) - Abstracts of the 5th Croatian Congress on Alzheimer’s Disease with International Participation / Šimić, Goran ; Mimica, Ninoslav - Zagreb : Denona, 2010, 111-111

Skup
5th Croatian Congress on Alzheimer's Diseases with International Participation

Mjesto i datum
Zadar, Hrvatska, 22.09.2010. - 25.09.2010

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
Informed consent; Alzheimer's dementia

Sažetak
The proportion of elderly population is in constant increase worldwide. About 5 fo of persons over the age of 65 and about 50 % over the age of 95 have Alzheimer's dementia (AD). This brings out the need to perform more clinical studies in the said field. Unfortunately, scientific progress in the prevention and treatment of dementia has been disappointingly modest. Informed consent requires a voluntary and informed decision by a competent person. Researchers have shown that even mild-to moderate Alzheimer's disease has significant impact on treatment consent capacity. Obtaining a legitimate informed consent from patients whose decision-making capacity is impaired, yet keeping in mind the ethical dilemmas, legal rights, and benefits of a potential participant, is the key problem. The public perception of the research enterprise as beneficent has recently been shaken by reports of investigator-pharmaceutical financial alliances that appear to threaten scientific objectivity. Therefore, before enrolment in the clinical trial and according to our clinical trial experience, there is a tendency to evaluate the consent competency of an AD patient by an independent medical professional (neurologist, psychiatrist of psychologist). The independent professional would not participate in the further research procedures, ensuring objectivity and avoiding possible conflict of interests. The empirical literature includes a number of instruments designed to evaluate participants' understanding of consent forms and/or 1 or more components of capacity to consent to research. Most of the published measures focus exclusively on the understanding of disclosed material ; only two of the published measures, the MacArthur Competence Assessment Tool for Clinical Research (MacCAT- CR) and the Informed Consent Survey, are designed to evaluate all four commonly recognized dimensions of capacity to consent to research (understanding, appreciation, reasoning, and expression of choice). Assesment of consent competency of persons with AD by the independent proffesional ensures the patient's autonomy, safeguards his rights and protects the integrity of the clinician-scientist.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

Napomena
Indexed / Abstracted in: Neuroscience Citation Index ; EMBASE / Excerpta Medica

POVEZANOST RADA