Pregled bibliografske jedinice broj: 504857
Myogenic regulatory factors expression in rat musculus masseter after injury
Myogenic regulatory factors expression in rat musculus masseter after injury // Abstracts of the 2nd International symposium of Clinical and Applied anatomy ; u: Anatomy 2010 ; 4 Suppl 1:42-42: International Journal of Experimental and Clinical Anatomy / Akkın, Salih Murat ; Çelik, Hakan Hamdi (ur.).
Istanbul: Deomed Medical Publishing, 2010. str. 42-42 (predavanje, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 504857 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Myogenic regulatory factors expression in rat musculus masseter after injury
Autori
Bajek, Snježana ; Nikolić, Marina ; Šoić-Vranić, Tamara ; Đudarić, Luka
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
Abstracts of the 2nd International symposium of Clinical and Applied anatomy ; u: Anatomy 2010 ; 4 Suppl 1:42-42: International Journal of Experimental and Clinical Anatomy
/ Akkın, Salih Murat ; Çelik, Hakan Hamdi - Istanbul : Deomed Medical Publishing, 2010, 42-42
Skup
International Symposium of Clinical and Applied Anatomy (2 ; 2010)
Mjesto i datum
Prag, Češka Republika, 09.07.2010. - 11.07.2010
Vrsta sudjelovanja
Predavanje
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
bupivacaine; masseter muscle; regulatory myogenic factors
Sažetak
Skeletal muscle is a dynamic system that responds quickly and adapts to changes in intrinsic and extrinsic stimuli. A whole repertoire of genes can be activated in response to these stimuli. The family of myogenic basic helix - loop - helix (bHLH) transcription factors (MyoD, myogenin, MRF4, Mif- 5) plays a major role in coordinating the muscle developmental program, as well as the process of adaptation. These factors contribute to the transcriptional activation of muscle genes during commitment and differentiation. The aim of this study was to determinate time course expression of MyoD and myogenin during regeneration in musculus masseter. All experiments were performed on male Sprague - Dowley rats. Histochemical, immunohistochemical and Western blot analyses were performed on masseter muscles. Regeneration process of skeletal muscles was induced by injection of bupivacain. Regeneration of masseter muscle caused a transcient upregulation of MyoD and myogenin. After reestablishment of normal muscle architecture there was no expression of MyoD and myogenin. The main conclusion of our investigation is that role of MyoD and myogenin is important in repair response of muscle fibers.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
POVEZANOST RADA
Projekti:
062-0000000-1352 - Utjecaj hiperbarične oksigenacije na regeneraciju skeletnog mišića i živca (Bajek, Snježana, MZOS ) ( CroRIS)
062-0000000-3559 - Uloga koštanih morfogenih proteina i inhibitora u nastanku osteofita čovjeka (Zoričić Cvek, Sanja, MZOS ) ( CroRIS)
Ustanove:
Medicinski fakultet, Rijeka
