Naslov
Malignant neuroleptic syndrome in psychopharmacotherapy of psychotic patients

Autori
Folnegović-Šmalc, Vera ; Folnegović, Zdenko ; Makarić, Gordan ; Mimica, Ninoslav

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
"Campaign on Schizophrenia 1995" - Workshop on: Critical Issues in the Treatment of Schizophrenia / Judd, LL ; Langer, SZ ; Mendlewicz, J ; Racagni, G ; Shibuya, T - Firenza : München : International Academy for Biomedical and Drug Research, 1995, 156-156

Skup
Campaign on Schizophrenia, Workshop on: Critical Issues in the Treatment of Schizophrenia

Mjesto i datum
Firenca, Italija, 10.05.1995. - 12.05.1995

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Malignant neuroleptic syndrome; psychopharmacotherapy; psychosis

Sažetak
In a ten-year follow-up study of 3602 psychotic patients hospitalized at the Clinical Department of Psychiatric Hospital Vrapce In Zagreb, the efficacy and tolerance of psychotropic drugs were evaluated. The average number of hospitalizations was 2.6 per patient. The authors present the structure of drugs administered in certain phases of treatment, with regard to all drugs administered simultaneously, and the nature of side effects that appeared in any phase of the treatment. A special attention was paid to diagnostic of malignant neuroleptic syndrome (MNS). It was found in 18 patients, all of whom belonged to the age group between 35 and 61 years. Before the onset of MNS in those patients, psychopharmacotherapy was applied over one week to more than a year. A tendency towards the relapse of MNS was found in some patients. In 20.2% of the subjects, clozapine was administered as monotherapy. None of them developed MNS, so the authors conclude that clozapine is a psychotropic drug of choice in the patients suspect of developing MNS.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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