Naslov
Utjecaj strukturne rigidnosti bisureanaftalenskih derivata na vezivanje aniona
(Influence of structure rigidity on anion binding of bisureanaphthalene derivatives)

Autori
Blažek, Vesna ; Mlinarić-Majerski, Kata ; Basarić, Nikola

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
XXII. HRVATSKI SKUP KEMIČARA I KEMIJSKIH INŽENJERA / - Zagreb, 2011

Skup
XXII. HRVATSKI SKUP KEMIČARA I KEMIJSKIH INŽENJERA

Mjesto i datum
Zagreb, Hrvatska, 13.02.2011. - 16.02.2011

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
vezianje aniona; urea; naftalenski derivati
(anion binding; urea; naphthalene derivatives)

Sažetak
Due to the involvement of anions in almost every biochemical process it is important to synthesize novel anion sensors with desired anion selectivity [1]. Many groups work on the design and synthesis of novel receptors characterized by better selectivity for anion complexation. Questions that still remain unanswered are mainly related to the geometry of the receptors, such as influence of molecular rigidity, or number of necessary binding sites for the desired selectivity. Recently we reported some examples of anion complexation by adamantyl dipyrromethane derivatives wherein recognition was influenced by molecular rigidity [2]. In search for receptors that would offer selectivity to biologically important oxo-anions such as phosphate, we focused our attention to urea derivatives [3]. Herein we report on anion binding ability of a series of bisureanaphthalene derivatives. The series is prepared in order to investigate the influence of structure rigidity to the binding selectivity. Therefore the anion binding of adamantyl bisurea derivatives was compared to the analogous host molecules wherein the urea moieties are separated by flexible alkyl linkers of the same length, and adamantane monourea derivative. The complexation was investigated by UV-vis, fluorescence and NMR spectroscopy [4].

Izvorni jezik
Engleski

Znanstvena područja
Kemija

POVEZANOST RADA