Naslov
Effects of maternal overweight/obesity on neonatal outcome

Autori
Juretić, Emilija ; Ilijić, Marcela ; Juras, Josip ; Anić, Sonja ; Vukelić, Vesna ; Pleša, Mirna

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni

Izvornik
XXXII. Alpe Adria meeting of perinatal medicine, Book of abstracts / Meir, Yoram - Bassano del Grappa, 2010, 21-21

Skup
XXXII. Alpe Adria meeting of perinatal medicine

Mjesto i datum
Bassano del Grappa, Italija, 15.10.2010. - 16.10.2010

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Nije recenziran

Ključne riječi
prekomjerna tjelesna masa; pretilost; neonatalni ishod
(overweight; obesity; neonatal outcome)

Sažetak
Background As the prevalence of obesity is rising exponentially worldwide, the overweight and obesity rate is also increasing among women of reproductive age. This is associated with increased risk of adverse outcomes for both mother and child. Objective Our goal was to assess the impact of maternal overweight/obesity on neonatal outcomes in glucose-tolerant women. Study design A retrospective cross-sectional study included pregnant women receiving prenatal and perinatal care at our hospital who also have a negative 2h/75 g oral glucose tolerance test. Women were divided into three groups according to their pregestational body mass index. Neonatal outcome variables were compared between groups. Results A total of 1, 284 women were divided into the following groups on the basis of BMI criteria: normal weight (NW, BMI 18-24.99 ; № 834), overweight (OW, BMI 25-29.99 ; № 321) and obese (OB, BMI>30 ; № 129). Women’s age differed significantly between groups NW and OW (29.79±5.41 kg and 31.12±5.31 kg respectively, p<0.01), weight gain during pregnancy differed between NW and OB (15.64±4.97 kg and 13.85±6.99 kg respectively, p<0.01) and parity between NW and the two other groups (first vs. subsequent pregnancies: NW 48.5 vs. 51.5% ; OW 35.2 vs. 64.8% ; OB 36.4 vs. 63.6% ; p<0.01). The rate of SC deliveries was significantly higher in OW and OB groups (NW 15.35% ; OW 27.41% ; OB 31.01%, p<0.01). There were more macrosomic (> 4 kg) babies (NW 15.59% ; OW 20.25% ; OB 24.03%, p<0.01) and LGA babies (>90 centile) in OW and OB group (NW 13.19% ; OW 20.25% ; OB 27.13%, p<0.01). Low Apgar scores in 1’ and 5’ were also more frequent in OW and OB groups as compared with NW group: NW Apgar 1’/5’ 10(7-10)/10(8-10), OB 10(1-10)/10(1-10), OW 10(2-10)/10(4-10). Perinatal asphyxia was diagnosed in 1.3% of NW babies, while in 3.01% of OW and 2.25% of OB babies. There was no significant difference among groups with respect to neonatal malformations or obstetric complications (shoulder dystocia) or birth trauma (clavicular fracture, cephalhematoma). Preterm delivery was more frequent in the OB group (14.0% vs. 9% in NW and 8.7% in OW group). Neonatal hypoglycemia and hypocalcemia occurred rarely in all three groups but perinatal infection was diagnosed more frequently in OB babies who also needed phototherapy more often. Conclusions OW and OB glucose-tolerant women deliver more macrosomic babies, as well as babies with lower Apgar scores and deliveries are more frequently done by SC. The rates of prematurity, hyperbilirubinemia and perinatal infection were higher in OB babies, although without statistical significance, than in those of the other two groups. There is the possibility that less weight gain in pregnancy can lower the risk of adverse pregnancy and adverse neonatal outcomes, so weight monitoring, dietary counselling and moderately increased physical activity should be recommended during pregnancy but every effort should be made to reduce pregestational weight in overweight and obese women.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA