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Pregled bibliografske jedinice broj: 493811

A ligand for the NKG2D receptor expressed by mouse CMV attenuates the virus, changes virus distribution and improves vaccine properties

Slavuljica, Irena; Busche, Andreas; Babić, Marina; Mitrović, Maja; Gašparović, Iva; Cekinović, Đurđica; Markova Car, Elitza; Pernjak Pugel, Ester; Ciković, Ana; Juranić Lisnić, Vanda et al.
A ligand for the NKG2D receptor expressed by mouse CMV attenuates the virus, changes virus distribution and improves vaccine properties // Annual meeting of the Austrian Society for Allergology and Immunology-Book of abstracts
Beč, 2010. str. 21-21 (poster, međunarodna recenzija, sažetak, znanstveni)

CROSBI ID: 493811 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
A ligand for the NKG2D receptor expressed by mouse CMV attenuates the virus, changes virus distribution and improves vaccine properties

Autori
Slavuljica, Irena ; Busche, Andreas ; Babić, Marina ; Mitrović, Maja ; Gašparović, Iva ; Cekinović, Đurđica ; Markova Car, Elitza ; Pernjak Pugel, Ester ; Ciković, Ana ; Juranić Lisnić, Vanda ; Britt, William J. ; Koszinowski, Ulrich ; Messerle, Martin ; Krmpotić, Astrid ; Jonjić, Stipan

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Annual meeting of the Austrian Society for Allergology and Immunology-Book of abstracts / - Beč, 2010, 21-21

Skup
Annual meeting of the Austrian Society for Allergology and Immunology

Mjesto i datum
Beč, Austrija, 03.12.2010. - 05.12.2010

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
MCMV; NKG2D; CMV vaccine

Sažetak
The authors propose a model where an engineered cytomegalovirus serves as a potential vaccine. Namely, a ligand for the strong activating NK cell receptors is inserted into a CMV-BAC, and this feature makes the virus strongly attenuated in vivo in both immunocompetent and immunodeficient hosts. Infection of mice with this virus however elicited strong, long-lasting protective immunity.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA

Projekti:
062-0621261-1263 - Molekularni mehanizmi citomegalovirusnog izmicanja imunološkom nadzoru (Jonjić, Stipan, MZOS ) ( CroRIS)
062-0621261-1268 - Uloga imunosubverzivnih citomegalovirusnih gena u latenciji (Krmpotić, Astrid, MZOS ) ( CroRIS)
062-0621261-1269 - Perinatalni citomegalovirusni encefalitis (Pernjak-Pugel, Ester, MZOS ) ( CroRIS)

Ustanove:
Medicinski fakultet, Rijeka

Profili:

Avatar Url Elitza Petkova Markova Car (autor)

Avatar Url Iva Gašparović-Curtini (autor)

Avatar Url Astrid Krmpotić (autor)

Avatar Url Ester Pernjak-Pugel (autor)

Avatar Url Đurđica Cekinović Grbeša (autor)

Avatar Url Vanda Juranić Lisnić (autor)

Avatar Url Irena Slavuljica (autor)

Avatar Url Maja Arapović (autor)

Avatar Url Stipan Jonjić (autor)

Avatar Url Marina Babić Čač (autor)

Avatar Url Ana Ciković (autor)

Citiraj ovu publikaciju:

Slavuljica, Irena; Busche, Andreas; Babić, Marina; Mitrović, Maja; Gašparović, Iva; Cekinović, Đurđica; Markova Car, Elitza; Pernjak Pugel, Ester; Ciković, Ana; Juranić Lisnić, Vanda et al.
A ligand for the NKG2D receptor expressed by mouse CMV attenuates the virus, changes virus distribution and improves vaccine properties // Annual meeting of the Austrian Society for Allergology and Immunology-Book of abstracts
Beč, 2010. str. 21-21 (poster, međunarodna recenzija, sažetak, znanstveni)
Slavuljica, I., Busche, A., Babić, M., Mitrović, M., Gašparović, I., Cekinović, Đ., Markova Car, E., Pernjak Pugel, E., Ciković, A. & Juranić Lisnić, V. (2010) A ligand for the NKG2D receptor expressed by mouse CMV attenuates the virus, changes virus distribution and improves vaccine properties. U: Annual meeting of the Austrian Society for Allergology and Immunology-Book of abstracts.
@article{article, author = {Slavuljica, Irena and Busche, Andreas and Babi\'{c}, Marina and Mitrovi\'{c}, Maja and Ga\v{s}parovi\'{c}, Iva and Cekinovi\'{c}, \DJur\djica and Markova Car, Elitza and Pernjak Pugel, Ester and Cikovi\'{c}, Ana and Jurani\'{c} Lisni\'{c}, Vanda and Britt, William J. and Koszinowski, Ulrich and Messerle, Martin and Krmpoti\'{c}, Astrid and Jonji\'{c}, Stipan}, year = {2010}, pages = {21-21}, keywords = {MCMV, NKG2D, CMV vaccine}, title = {A ligand for the NKG2D receptor expressed by mouse CMV attenuates the virus, changes virus distribution and improves vaccine properties}, keyword = {MCMV, NKG2D, CMV vaccine}, publisherplace = {Be\v{c}, Austrija} }
@article{article, author = {Slavuljica, Irena and Busche, Andreas and Babi\'{c}, Marina and Mitrovi\'{c}, Maja and Ga\v{s}parovi\'{c}, Iva and Cekinovi\'{c}, \DJur\djica and Markova Car, Elitza and Pernjak Pugel, Ester and Cikovi\'{c}, Ana and Jurani\'{c} Lisni\'{c}, Vanda and Britt, William J. and Koszinowski, Ulrich and Messerle, Martin and Krmpoti\'{c}, Astrid and Jonji\'{c}, Stipan}, year = {2010}, pages = {21-21}, keywords = {MCMV, NKG2D, CMV vaccine}, title = {A ligand for the NKG2D receptor expressed by mouse CMV attenuates the virus, changes virus distribution and improves vaccine properties}, keyword = {MCMV, NKG2D, CMV vaccine}, publisherplace = {Be\v{c}, Austrija} }

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