Pregled bibliografske jedinice broj: 491366
7-Chloro-3-methyl-3-4-dihydro-2H-1,2,4 benzothiadiazine S,S-dioxide (IDRA 21): a benzothiadiazine derivative that enhances cognition by attenuating DL-alpha-amino-2,3- dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid (AMPA) receptor desensitization
7-Chloro-3-methyl-3-4-dihydro-2H-1,2,4 benzothiadiazine S,S-dioxide (IDRA 21): a benzothiadiazine derivative that enhances cognition by attenuating DL-alpha-amino-2,3- dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid (AMPA) receptor desensitization // The Journal of pharmacology and experimental therapeutics, 272 (1995), 300-309 (međunarodna recenzija, članak, znanstveni)
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Naslov
7-Chloro-3-methyl-3-4-dihydro-2H-1,2,4
benzothiadiazine S,S-dioxide (IDRA 21): a
benzothiadiazine derivative that enhances
cognition by attenuating DL-alpha-amino-2,3-
dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid
(AMPA) receptor desensitization
Autori
Živković, Ilija ; Thompson, D.M. ; Bertolino, M. ; Uzunov, D. ; DiBella, M. ; Costa, E. ; Guidotti, A.
Izvornik
The Journal of pharmacology and experimental therapeutics (0022-3565) 272
(1995);
300-309
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
IDRA 21 ; benzothiadiazine ; AMPA receptor
Sažetak
IDRA 21 given orally presumably crosses the blood brain and acts stereoselectively on specific receptors that were operative during behevioral procedure.IDRA 21 appears to be related to ist ability to potentiate AMPA activated currents. One can suggest that IDRA 21 improves cognition by acting on a stereoselective site of AMPA receptor.
Izvorni jezik
Engleski
Znanstvena područja
Farmacija
Citiraj ovu publikaciju:
Časopis indeksira:
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
Uključenost u ostale bibliografske baze podataka::
- Medical and Pharmaceutical Biotechnology Abstracts
