Naslov
Cerebral Hemodynamics In Patients With Type II Of Diabetes Mellitus And Assessment Of Transcranial Dopler

Autori
Bitunjac, Milan ; Dikanović, Marinko ; Lojen, Gordana ; Ažman, Dražen ; Šapina, Lidija ; Kadojić, Dragutin

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Skup
42nd Danube Symposium for Neurological Science and Continuing Education

Mjesto i datum
Zagreb, Hrvatska, 21.10.2010. - 23.10.2010

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Cerebral Hemodynamics ; Type II Diabetes Mellitus ; Transcranial Dopler

Sažetak
Background: Diabetics have a 3-fold risk for cardiovascular diseases compared with non- diabetics. This study was designed to evaluate cerebral hemodynamic changes related to type 2 diabetes mellitus (DM) with transcranial Doppler ultrasonography (TCD). TCD is a highly sensitive and specific method of quick bedside assessment of cerebrovascular circulation hemodynamics. Patients and Methods: In a prospective study, we compared a group of 100 patients with the diagnosis of type 2 diabetes mellitus (aged 48 to 67 years) and an age- and sex-matched control group of 100 healthy subjects without diabetes mellitus. We measured flow velocities (Vm) and the Gosling pulsatility index (PI) of the middle cerebral artery (MCA). Results: The rate of TCD abnormalities was significantly higher in diabetic patients than in healthy control subjects (55% vs. 11%, P<0.05). The PI was significantly higher in diabetic patients than in healthy controls (P<0.001). Atherosclerotic changes were found in 34.0% and 71.4% of patients suffering from diabetes for <5 and ≥ 5 years, respectively. Conclusion: This study suggests that TCD is a useful marker for the detection of diabetic cerebrovascular changes. The duration and type of diabetes were found to have an impact on the development of pathologic cerebrovascular changes.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA