Novel substituted 1-iminoisoindoline derivatives : synthesis, structure determination and antiproliferative activity

Sović, Irena; Stilinović, Vladimir; Kaitner, Branko; Kraljević Pavelić, Sandra; Bujak, Maro; Čuljak, Katarina; Novak, Predrag; Karminski-Zamola, Grace

doi:10.1016/j.molstruc.2011.09.017

Pregled bibliografske jedinice broj: 490037

Novel substituted 1-iminoisoindoline derivatives : synthesis, structure determination and antiproliferative activity

Sović, Irena; Stilinović, Vladimir; Kaitner, Branko; Kraljević Pavelić, Sandra; Bujak, Maro; Čuljak, Katarina; Novak, Predrag; Karminski-Zamola, Grace

Novel substituted 1-iminoisoindoline derivatives : synthesis, structure determination and antiproliferative activity // Journal of molecular structure, 1006 (2011), 1-3; 259-265 doi:10.1016/j.molstruc.2011.09.017 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 490037 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Novel substituted 1-iminoisoindoline derivatives : synthesis, structure determination and antiproliferative activity

Autori
Sović, Irena ; Stilinović, Vladimir ; Kaitner, Branko ; Kraljević Pavelić, Sandra ; Bujak, Maro ; Čuljak, Katarina ; Novak, Predrag ; Karminski-Zamola, Grace

Izvornik
Journal of molecular structure (0022-2860) 1006 (2011), 1-3; 259-265

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
1-imino isoindoline derivatives ; synthesis ; crystal structure determination ; spectroscopic characterization ; thermal analysis

Sažetak
Novel derivatives of isoindoline, N-phenyl-1-iminophenylisoindoline 6, N-(4-methylphenyl)-1-imino-(4-methylphenyl)-isoindoline 7, N-(pyridin-2-yl)-1-imino-(pyridin-2-yl)-isoindoline 8 and N-(5-methylpyridin-2-yl)-1-imino(5-methylpyridin-2-yl)-isoindoline 9 were prepared by the reaction of condensation of phthalaldehide and corresponding amines. Structures of all compounds had been studied using 1H and 13C NMR, IR, MS and UV/Vis spectroscopy. The crystal and molecular structures of 7, 8 and 9 were determined by X-ray diffraction on single crystals. In all three molecules the isoindoline system and its N-substituent are approximately coplanar. The crystal structures comprise of discrete molecules linked only by weak C—H ••• N interactions in the case of 8 and 9.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biologija

POVEZANOST RADA

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