Pregled bibliografske jedinice broj: 487087
Rocuronium attenuates oculocardiac reflex during squint surgery in children anesthetized with halothane and nitrous oxide.
Rocuronium attenuates oculocardiac reflex during squint surgery in children anesthetized with halothane and nitrous oxide. // Acta Anaesthesiol Scandinavica, 48 (2004), 1351-5 (podatak o recenziji nije dostupan, članak, ostalo)
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Naslov
Rocuronium attenuates oculocardiac reflex during squint surgery in children anesthetized with halothane and nitrous oxide.
Autori
Karanović, Nenad ; Jukić, Marko ; Carev, Mladen ; Kardum, Goran ; Đogaš Zoran
Izvornik
Acta Anaesthesiol Scandinavica (0001-5172) 48
(2004);
1351-5
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, ostalo
Ključne riječi
Halothane; inhalational anesthesia; muscle relaxants;
Sažetak
Background: The oculocardiac reflex (OCR) may be activated during squint surgery. The aim of this study was to test whether rocuronium 0.4mg kg1 could reduce the frequency of OCR, and also whether a single dose of succinylcholine 1mgkg1 could affect the frequency of OCR during anesthesia with halothane in a nitrous oxide/oxygen mixture. Methods: A total of 161 ASA I children, 3—10 years old, undergoing elective surgery of the medial rectus muscle (MRM) were randomly assigned to three groups. Group R (n¼51), received 0.4mgkg1 of rocuronium intravenously before endotracheal intubation. Group S (n¼58) received 1mgkg1 of succinylcholine. Group C (controls, n¼52) received no relaxant. Oculocardiac reflex was defined as a reduction in heart rate (HR)>¼15% and/or the appearance of any other arrhythmias, during manipulation of the MRM. Analysis of variance (ANOVA), chi-squared, Kruskal—Wallis, and Student’s t-tests were used for statistical analysis ; P<0.05 was considered statistically significant. Results: In group R, OCR occurred in 15/51 (29%) of children, in group S in 31/58 (53%), and in group C in 23/52 (44%) (2¼6.46, P¼0.049). In group R, the incidence of arrhythmias such as nodal rhythms, supraventricular and ventricular premature beats was 6%, compared with 22% in group S and 19% in group C (2¼6.01, P¼0.040). However, there was no reduction in the occurrence of bradycardia (2¼0.16, P¼0.924)., Conclusion: Rocuronium reduced the frequency of OCR, mainly by reducing the incidence of supraventricular and ventricular premature beats.
Izvorni jezik
Engleski
