Pregled bibliografske jedinice broj: 476761
Native and tabun-inhibited cholinesterase interactions with oximes
Native and tabun-inhibited cholinesterase interactions with oximes // The Proceedings of the Chemical and Biological Medical Treatment Symposium - CBMTS - Industry VI "The Fifth World Congress on Chemical, Biological and Radiological Terrorism" / Bokan, Slavko ; Orehovec, Zvonko ; Price, Barbara (ur.).
Kaneohe (HI): Applied Science and Analysis - ASA, 2010. str. 156-158 (poster, međunarodna recenzija, cjeloviti rad (in extenso), znanstveni)
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Naslov
Native and tabun-inhibited cholinesterase interactions with oximes
Autori
Kovarik, Zrinka ; Katalinić, Maja ; Šinko, Goran
Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni
Izvornik
The Proceedings of the Chemical and Biological Medical Treatment Symposium - CBMTS - Industry VI "The Fifth World Congress on Chemical, Biological and Radiological Terrorism"
/ Bokan, Slavko ; Orehovec, Zvonko ; Price, Barbara - Kaneohe (HI) : Applied Science and Analysis - ASA, 2010, 156-158
Skup
The Fifth World Congress on Chemical, Biological and Radiological Terrorism
Mjesto i datum
Cavtat, Hrvatska, 05.04.2009. - 10.04.2009
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
acetylcholinesterase; antidote; bioscavenger; butyrylcholinesterase; nerve agents; tabun; oxime; treatment
Sažetak
We tested oximes varying in the type of ring (pyridinium and/or imidazolium), the length and type of the linker between rings, and in the position of the oxime group on the ring to find more effective oximes to reactivate tabun-inhibited human erythrocyte AChE and plasma BChE. Herein we bring an overview of in vitro interactions of native and tabun-inhibited AChE and BChE with oximes relating molecular properties of oximes to their reactivation potency
Izvorni jezik
Engleski
Znanstvena područja
Kemija
POVEZANOST RADA
Projekti:
022-0222148-2889 - Interakcije organofosfata, karbamata i određenih liganada s esterazama (Kovarik, Zrinka, MZOS ) ( CroRIS)
Ustanove:
Institut za medicinska istraživanja i medicinu rada, Zagreb
