Pregled bibliografske jedinice broj: 47260
Phenanthridinium cyclobisintercalands. Fluorescence sensing of AMP and selective binding to single-stranded nucleic acids
Phenanthridinium cyclobisintercalands. Fluorescence sensing of AMP and selective binding to single-stranded nucleic acids // Tetrahedron Letters, 42 (2001), 6779-6783 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 47260 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Phenanthridinium cyclobisintercalands. Fluorescence sensing of AMP and selective binding to single-stranded nucleic acids
Autori
Piantanida, Ivo ; Palm, Barbara Susanne ; Čudić, Predrag ; Žinić, Mladen ; Schneider, Hans-Joerg
Izvornik
Tetrahedron Letters (0040-4039) 42
(2001);
6779-6783
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
phenanthridinium; receptor; cyclobisintercaland; nucleic acid
Sažetak
Macrocyclic ligands 1 and 2 containing two positively charged phenanthridinium units and aminobisacetylenic bridges, exhibit significantly higher affinity toward singlestranded than doublestranded polynucleotides. The ligands bis-intercalate into the former and show non-intercalative interactions with the latter type of nucleic acids. Both ligands differentiate AMP from the GMP or UMP by significant fluorescence emission increase upon complexation of the first nucleotide in water (log Ks of 1:1 and 1:2 complexes 5.8 and 1.4, respectively) while only slight emission change is observed in titrations with GMP and UMP.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
