Naslov
Focused high risk-population screening for carotid stenosis and retinal microangiopathia after radiotherapy for laryngeal carcinoma

Autori
Strenja-Linić, Ines ; Vojniković, Božidar ; Čaljkušić-Mance, Tea ; Tićac, Robert ; Bonifačić, David ; Kovačević, Damir

Izvornik
Collegium Antropologicum (0350-6134) 34 (2010), S2; 49-52

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
carotid artery stenosis; retinal microangiopathia; laryngeal carcinoma; radiotherapy

Sažetak
Carotid artery stenosis (CAS) is one of the major complications of external irradiation (radiotherapy, RT) for laryngeal carcinoma. Considering amaurosis fugax is often one of the first signs of significant CAS our focus was to determine weather patients with postirradiation CAS also develop ocular microangiopathy as a result of insufficient ophthalmic circulation. In our study Carotid Duplex ultrasound scans revealed that 33, 33 % of patients had significant radiation – induced CAS. The majority (over 85, 71%) of radiation-induced CAS had more than one atherosclerotic plaque including any degree of stenosis in the RT group, and had significantly more than that of the control group . Microangiopathic changes were documented only with the patients that have had increased cerebrovascular risk – DM and arterial hypertension.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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