Naslov
Magnesium in Patients with Bipolar Disorders

Autori
Ruljančić, Nedjeljka ; Bronić, Ana ; Rogić, Dunja

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Clinical Chemistry and Laboratory Medicine(Abstracts Book) / - , 2005, A78-A78

Skup
International Swiss MedLab and 8th Alps Adria Congress

Mjesto i datum
Luzern, Švicarska, 05.10.2004. - 09.10.2004

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
magnezij; bipolarni poremećaj
(magnesium; bipolar disorders)

Sažetak
AIM To determine the concentration of total blood magnesium (tMg) and ionized magnesium (iMg) in serum of patients with bipolar disorder treated by maintenance therapy lithium carbonate (1, 2). METHODS The concentration of tMg was measured by spectrophotometric method (reference interval 0, 70 mmol/l – 1, 10 mmol/l) while the concentration of iMg was measured by ion-selective electrodes (reference interval 0, 53 mmol/l-0, 67 mmol/l). Serum of 33 patients, 30 women and 3 men, aged between 26 and 53 was tested. All of our patients were in maintenance therapy interval (0, 60-1, 2 mmol/l). The concentration of lithium carbonate in the serum was measured by flame photometry. RESULTS In all patients the obtained concentration of tMg ranged from 0, 79 mmol/l to 1, 02 mmol/l (average level 0, 90 mmol/l) and the concentration of iMg ranged from 0, 53mmol/l to 0, 77 mmol/l (average level 0, 61 mmol/l). iMg in 26/33 patients was in reference interval while higher blood levels of iMg (higher then 0, 67mmol/l) were seen in 7/33 patients.CONCLUSION Our results show that normomagnesemia measured as tMg is a common finding in patients with bipolar disorder, but when measured as iMg, about 21% patients no longer show to be normomagnesemic. This findings imply that the measurement of iMg is preferred above the routinely measured tMg.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

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