Naslov
Bone mineral density in men with urolithiasis

Autori
Cvijetić, Selma ; Tucak, Antun ; Babić Ivančić, Vesna ; Dekanić Ožegović, Darinka

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni

Izvornik
Kidney Stones / Borghi, Loris ; Meschi, Tiziana ; Briganti, Angelo ; Schianchi, Tania ; - Parma : Editoriale Bios, 1999, 441-443

Skup
European Symposium on Urolithiasis

Mjesto i datum
Parma, Italija, 09.06.1999. - 12.06.1999

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Urolithiasis; men; hypercalciuria

Sažetak
Aim:to determine the bone mineral denisty in stone formers with and without hypercalciuria and to compare the results to the healthy controls. Subjects: 36 men with urolithiasis, mean age 42.9 +/- 8.5 years and 17 controls, aged 35.2 +/- 7.4 years. Methods: anthropometric measurements were performed (height, weight, body mass index - BMI). Laboratory analysis included serum and 24 hour urinary calcium. Bone mineral density (BMD) were measured in lumbar spine and femoral neck by dual-energy absorptiometry and in the radius by single-photon absorptiometry. Results: 7 patients had hypercalciuria (24 hour urinary calcium over 7.5 mmol). The mean BMD in patients with hypercalciuria was 1.150 +/- 0.156 g/cm2 in spine; 1.048 +/- 0.151 g/cm2 in femoral neck and 0.721 +/- 0.057 g/cm2 in radius. Spinal osteopenia was found in 5 hypercalciuric patients, femoral neck osteopenia in two patients and one patient with hypercalciuria had osteoporosis in radius. Comparing to controls, hypercalciuric patients had significantly lower BMD in spine (p<0.05) and in radius (p<0.01). Normocalciuric stone formers had significantly lower BMD in radius (p<0.05) comparing to controls. Multiple regression analysis showed significant association between calcium urinary excretion and BMD in spine and radius. Conclusion: increased calcium excretion in patients with urolithiasis is an important risk factor of decreased bone density, thus stone formers are exposed to a greater risk for developing osteoporosis.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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