Naslov
Quality of the cardiovascular drugs prescribing in Zagreb during the period 2001-2004

Autori
Štimac, Danijela ; Čulig, Josip ; Vukušić, Ivan ; Cattunar, Albert ; Stojanović, Dražen

Izvornik
Medicinski glasnik Ljekarske komore Zeničko-dobojskog kantona (1840-0132) 6 (2009), 1; 118-124

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
cardiovascular drugs; utilisation; ATC/DDD methodology; Zagreb

Sažetak
Aim To investigate the outpatient utilisation of cardiovascular drugs in Zagreb, during the 2001-2004 period, and to identify the possible association between the increase in the utilisation of particular drug groups and decrease in the number of hospital admissions. Methods The number of DDD per thousand inhabitants per day (DDDs/TID) was calculated from data on the number and size of dispensed drug packages, obtained from the Zagreb Pharmacies. Drug Utilisation 90% (DU90%) method was used on assessment of drug prescribing quality. Results Total utilisation of the cardiovascular drugs was high in Zagreb during the 2001-2004 period (between 402.9 DDDs/TID and 406.9 DDDs/TID). Agents acting on the renin-angiotensin system (C09) (121.3 DDDs/TID) and calcium channel blockers (C08) (87.5 DDDs/TID) accounted for more than 50% of drugs used for the treatment of hypertension in 2004. The greatest utilisation increase was observed for statins (78.3%). Comparison of DU90% segment between 2001 and 2004 revealed pentoxifylline and amiodarone to be absent, whereas cilazapril and ramipril in their combination with HCTZ, bisoprolol, valsartan and losartan alone or in their combination with HCTZ were added in 2004, DU90% segment still contain doxazosin and propafenone, which had no grounds in therapeutic guidelines. Conclusion The outpatient utilisation of cardiovascular drugs was high during the 2001-2004 period. The utilization pattern was improved. The result was a decrease in the number of hospital admissions for main cardiovascular events.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Javno zdravstvo i zdravstvena zaštita

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