Naslov
Continuous Wound Infusion With Levobupivacaine After Total Abdominal Hysterectomy With Bilateral Salpingo-Oophorectomy

Autori
Marić, Stela ; Stefančić, Ljilja ; Supić Krleža, Dubravka ; Misir Šitum, Stanka ; Brozović, Gordana ; Zdravčević Šakić, Kata

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstracts of the XXVII Annual Congress of the European Society of Regional Anaesthesia (ESRA) & Pain Therapy. U: Regional anesthesia and pain medicine 33(5), S1 / - , 2008, 161-161

Skup
Annual Congress of the European Society of Regional Anaesthesia & Pain Therapy

Mjesto i datum
Genova, Italija, 24.09.2008. - 27.09.2008

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
levobupivacine ; wound infilatration

Sažetak
Blockade of nociceptive afferents by the use ofcontinuous wound infiltration with local anesthetics may be beneficial in a postoperative multimodal pain management after total abdominal hysterectomy (TAH) with bilateral salpingo- oophorectomy (BSO). The efficiency of continuous wound infusion with local anesthetic is still controversial. The role of continuous wound infusion of levobupivacaine for pain relief and postoperative recovery was evaluated. Fifty patients were included in the randomized, double- blinded, placebo-controlled trial. On completion of the operation, a multiorifice 20-gauge epidural catheter was placed above the superficial abdominal fascia such that the tip was at the midpoint of the surgical wound. Patients were divided in two equal groups. Group L received through the catheter 0.25% levobupivacaine with 8 ml bolus followed by an infusion of 7 ml/h during 48 h and Group S received 0.9%NaCl at the same protocol. Simultaneously, all patients received diclofenac 75 mg every 12 h for 48 h and patient- controlled analgesia with intravenous morphine on demand. The safety and efficiency of the technique were investigated, postoperative visual analogue pain scores, morphine requirements at 6, 12, 24 and 48 h postoperatively, and time to recovery of bowel function were analyzed. Satisfactory analgesia was achieved in both groups. Levobupivacaine infusion significantly reduced morphine consumption during the first 48 h in Group L (6.91 mg +/- 3.17) in comparison to Group S (50.61 mg +/-14.02) (P < 0.001). Nausea and vomiting were less present in Group L. Time to recovery of bowel function was significantly reduced in Group L. No side effects were observed. Postoperative pain control with continuous wound infusion of 0.25% levobupivacaine after TAH with BSO provides effective analgesia, decreases opioid requirements and reduces time to recovery of bowel function.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA