Naslov
Depressive disorders and comorbidity: somatic illness vs. side effect

Autori
Uzun, Suzana ; Kozumplik, Oliver ; Topić, Radmila ; Jakovljević, Miro

Izvornik
Psychiatria Danubina (0353-5053) 21 (2009), 3; 391-398

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Depressive disorder; Comorbidity; Somatic illness
(depressive disorder; comorbidity; somatic illness)

Sažetak
BACKGROUND: The rate of comorbid depression and medical illness varies from 10 to 40%. Patients with depressive disorder compared to general population more often have cardiovascular and cerebrovascular disorders, diabetes, irritable bowel syndrome, and some types of tumor. Side effects of mental health medications may appear in a form that is very similar to clinical presentation of somatic illness. Side effects that appear during treatment of depressive disorder, e. g. cardiovascular, gastrointestinal, movement disorders, etc., may provoke certain diagnostic issues regarding origin of such symptoms (somatic illness vs. side effect). The aim of this article is to review literature regarding comorbidity of depressive disorder and somatic illness and to point at possible diagnostic problems in differentiating comorbid somatic illness and side effects of antidepressants. CONTENT ANALYSIS OF LITERATURE: Literature research included structured searches of Medline and other publications on the subject of comorbidity of depressive disorder and somatic disorders and possible diagnostic problems in differentiating comorbid somatic illnesses from side effects of antidepressants. CONCLUSION: Comorbidity between depressive disorder and various somatic disorders appears often. Investigations suggest that depressive disorder is underdiagnosed in such cases. Side effects of antidepressants are sometimes very hard to differentiate from symptoms of somatic illness, which may lead to diagnostic issues. Bearing in mind frequent comorbidity between of depressive and somatic disorders, early recognition of such comorbidity is important, as well as the selection of antidepressant. It is important to recognize depressive disorder in patients with somatic illnesses, as well as somatic illness in patients primarily treated because of depressive disorder.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA