Naslov
Is visceral adiposity predictor of aortic diseases?

Autori
Hrabak Paar, Maja ; Štern-Padovan, Ranka

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni

Izvornik
European Congress of Radiology ECR 2010, Electronic Presentation Online System (EPOS) / - , 2010

Skup
European Congress of Radiology ECR 2010

Mjesto i datum
Beč, Austrija, 04.03.2010. - 08.03.2010

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
visceral fat; atherosclerotic plaque; abdominal aortic aneurysm

Sažetak
Purpose: To evaluate the relationship between the amount and distribution of abdominal adipose tissue with development of abdominal aortic aneurysm (AAA) and atherosclerotic changes of the aorta. Methods and Materials: MSCT angiography of the aorta was performed in 94 patients with AAA and in 94 control subjects. Total, visceral and subcutaneous abdominal fat areas were measured on a single axial CT scan at the level of umbilicus and compared between the groups by the t-test for independent samples. In the control group atherosclerotic plaques of aortic segments were semiquantitatively graded (grade 1 – no wall thickening, grade 2 – wall thickening without lumen irregularity, grade 3 – wall thickening with lumen irregularity and minimal calcifications, grade 4 – high plaque burden and abundant calcifications), and their relationship with abdominal fat areas was evaluated. Results: We found no relationship between AAA development and total and visceral fat areas, while subcutaneous abdominal fat area was significantly smaller in the AAA group than in the control group (189±84 vs. 225±90cm2 ; t=-2.88 ; p=0.004 ; 95% CI -61.7 to -11.5). In the control group positive relationship between visceral fat area and atherosclerotic lesions was seen (rs=0.29, p=0.005 for the ascending aorta, rs=0.24, p=0.02 for the aortic arch, rs=0.32, p=0.002 for the descending thoracic and abdominal aorta). There was neither protective nor harmful effect of subcutaneous fat tissue on development of aortic atherosclerosis. Conclusion: Visceral adiposity is predictor of aortic atherosclerosis, but not of AAA development, indicating that these aortic diseases are caused by different pathophysiological mechanisms.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA